Seow Tien Yeo


SeowTien is a Research Fellow in Health Economics at the Centre for Health Economics and Medicines Evaluation (CHEME). She holds a BSc. (Hon.) in Food Science and Nutrition from the National University of Malaysia and a MSc. degree in Public Health and Health Promotion from Bangor University. She has twelve years research experience. Her primary research interests are economic evaluation alongside clinical randomised controlled trial and preferences of people in health care settings. She is also a staff PhD candidate exploring the health economics of EUS staging of gastro-oesophageal cancer and the current clinical practice in Wales (funded by Tenovus Cancer Care). She is multilingual – She can speak six languages (English, Mandarin, Malay, Hokkien, Cantonese and Japanese) and a bit of Welsh.

Research Interests

  • Economic evaluation alongside randomised controlled trial
  • Economics of Cancer Care
  • Individuals’ preferences for healthcare service delivery


  • Economic evaluations e.g. cost-effectiveness analysis, cost-utility analysis, cost-consequences analysis.
  • Discrete Choice Experiment / Discrete Choice Modelling

Current Projects

As Co-PI / lead health economist / co-lead health economist –

  • PCI-QOL study (co-PI; funded by the NIHR Research for Patient Benefit) – A cluster randomised controlled trial looking at improving quality of life through the routine use of the Patient Concerns Inventory (PCI) for head and neck cancer patients (PCI-QOL).
  • WICKED study (funded by Cancer Research Wales) – The development and evaluation of primary care interventions to expedite the diagnosis of symptomatic cancer in Wales
  • TOPCAT-G study (funded by BCUHB) – A feasibility study comparing nurse-led follow-up care after gynaecological cancer treatment with standard, hospital-based, medical follow-up care;
  • Oral Health Pilot DCE study – A pilot discrete choice experiments (DCEs) study exploring patients’ preferences for oral healthcare service delivery and the feasibility of gaining preference of patients using DCE.

Previous Projects

  • Trismus Trial (funded by the NIHR Research for Patient Benefit) - A feasibility study examined the change in jaw opening between pre and post radiotherapy in patients with head and neck cancer using Therabite as compared with wooden spatula (standard care);
  • ELCID trial (funded by the National Awareness and Early Diagnosis Initiative (NAEDI) – Research Core Funding Partners) – A feasibility study explored early lung cancer identification and diagnosis with an aim to identify whether 'extra-NICE' guidelines improve lung cancer survival as compared with current 'NICE' guideline;
  • TOPCAT-P (funded by Macmillan Cancer Support) – A feasibility study comparing nurse-led holistic needs assessment care after prostate cancer treatment with standard usual care;
  • EPIC trial (funded by the NIHR SDO programme) – Evidence into Practice: evaluating a child-centred intervention for diabetes medicine management;
  • COGNATE trial (funded by NIHR HTA) – Cancer of the Oesophagus or Gastricus: New Assessment of the Technology of Endosonography;
  • Diabetic Retinopathy (DR) study (funded by the Welsh Office of Research and Development (WORD)) – A study that explored whether the annual screening interval for diabetic retinopathy can be extended in patients with no retinopathy. Alongside this, she has conducted a sub-study of the DR study using a Discrete Choice Experiment (DCE) approach, to elicit patients’ preferences for different aspects of the DR screening service;
  • Systematic review of effectiveness and cost-effectiveness of public interventions to promote mental well-being in people aged 65 and above, funded by NICE;
  • MortISE study (funded by the Chief Scientist Office ) – Steroid injections (methylprednisolone) in the treatment of Morton's neuroma: patient-blind randomised controlled trial
  • Incredible Years' follow-up study (funded by the Health Foundation) – Long-term effectiveness of a parenting intervention for children at risk of developing conduct disorders
  • LILAC study (funded by WORD for Health and Social Care) – Incredible Years parent training support for foster carers in Wales: a multi-centre feasibility study.
  • Orphan drugs study (funded by Actelion) – A study of drugs for exceptionally rare diseases: do they deserve special status for funding?
  • Fruit project (funded by CHEME) – A costing and feasibility study to promote fruit consumption in primary school children in Anglesey, North Wales.

Other Research Activities

  • Mentors/Supports CHEME PhD students
  • Supports NHS staffs undertaking research across the Betsi Cadwaladr University Health Board (BCUHB)


Lead and teach postgraduate classes on discrete choice modelling for students undertaking MSc in Public Health and Health Promotion in the School of Healthcare Sciences, Bangor University.


  1. Seow Tien Yeo, Nathan Bray, Hasan Haboubi, Zoe Hoare, Rhiannon Tudor Edwards. Economic evidence for EUS staging in patients with gastro-oesophageal cancer (GOC): protocol for a systematic review. PROSPERO 2016:CRD42016043700 Available from:

  2. Nathan Bray, Seow Tien Yeo, Jane Noyes, Nigel Harris, Rhiannon Tudor Edwards. Prioritising wheelchair services for children: a pilot discrete choice experiment to understand how child wheelchair users and their parents prioritise different attributes of wheelchair services. Pilot and Feasibility Studies, 2016, 2:32. DOI 10.1186/s40814-016-0074-y.

  3. Hughes D, Charles J, Dawoud D, Edwards RT, Holmes E, Jones C, Parham P, Plumpton C, Ridyard C, Lloyd-Williams H, Wood E, Yeo ST. Conducting Economic Evaluations Alongside Randomised Trials: Current Methodological Issues and Novel Approaches. Pharmacoeconomics, 2016 Jan 11. DOI 10.1007/s40273-015-0371-y.

  4. Edwards RT, Yeo ST, Russell D, Thomson CE, Beggs I, Gibson J.N.A, McMillan D, Martin DJ, Russell IT. Cost-effectiveness of steroid (methylprednisolone) injections versus anaesthetic alone for the treatment of Morton’s neuroma: economic evaluation alongside a randomised controlled trial (MortISE trial). Journal of Foot and Ankle Research, 2015, 8(6):1-11. DOI:10.1186/s13047-015-0064-y.

  5. Jane P Noyes, Lesley Lowes, Rhiannon Whitaker, Davina Allen, Cynthia Carter, Rhiannon T Edwards, Joanne Rycroft-Malone, Janice Sharp, Deborah Edwards, Llinos Haf Spencer, Yvonne Sylvestre, Seow Tien Yeo and John W Gregory. Evidence into practice: The ‘EPIC Project’: Developing and evaluating a child-centered intervention for diabetes medicine management using mixed-methods and a multi-centre Randomised Controlled Trial. National Institute for Health Research (NIHR), Health Services and Delivery Research, 2014, 2(8). DOI: 10.3310/hsdr02080.

  6. Christopher N Hurt, Kirsty Roberts, Trevor K Rogers, Gareth O Griffiths, Kerry Hood, Hayley Prout, Annmarie Nelson, Jim Fitzgibbon, Allan Barham, Emma Thomas-Jones, Rhiannon Tudor Edwards, Seow Tien Yeo, William Hamilton, Angela Tod and Richard D Neal A feasibility study examining the effect on lung cancer diagnosis of offering a chest X-ray to higher-risk patients with chest symptoms:protocol for a randomized controlled trial. Trials, 2013, 14:405. DOI:10.1186/1745-6215-14-405.

  7. I.T. Russell, R.T.Edwards, A.E. Gliddon, D.K.Ingledew, D.Russell, R. Whitaker, S.T.Yeo, S.E. Attwood, H. Barr, S. Nanthakumaran and K.G.M. Park. Cancer of Oesophagus or Gastricus- New Assessment of Technology of Endosonography (COGNATE): report of pragmatic randomised trial. HTA, 2013, 17(39). DOI: 10.3310/hta17390.

  8. Thomson C.E., Beggs I., Martin D.J., McCaldin D., Edwards R.T., Russell D., Yeo S.T., Russell I.T. and Gibson J.N.A. Methylprednisolone injections for the treatment of Morton Neuroma: A patient-blinded randomized trial. J Bone Joint Surg Am, 2013, 95, 790-798. DOI: 10.2106/JBJS.I.01780.

  9. S.T.Yeo, R.T.Edwards, S.D.Luzio, J.M.Charles, R.L.Thomas, J.M.Peters, D.R.Owens. Diabetic retinopathy screening: perspectives of people with diabetes, screening intervals and costs of attending screening. Diabetic Medicine, 2012, 29(7), 878-885. DOI: 10.1111/j.1464-5491.2012.03637.x.

  10. S.T.Yeo, R.T.Edwards, E.A.Fargher, S.D.Luzio, R.L.Thomas, D.R.Owens. Preferences of people with diabetes for diabetic retinopathy screening: A discrete choice experiment. Diabetic Medicine, 2012, 29(7), 869-877. DOI: 10.1111/j.1464-5491.2012.03636.x.

  11. The Diabetic Retinopathy Team. Can the annual screening interval for diabetic retinopathy be extended in patients with no retinopathy? Wales Office for Research and Development in Health and Social Care (WORD) report (reference no.: H07-3-042), 18th March 2011.

  12. I Russell, S Attwood, H Barr, R Tudor Edwards, A Gliddon, D Ingledew, K Park, D Russell, S T Yeo, R Whitaker, on behalf of the COGNATE trial team. Society for Social Medicine abstracts, Cancer: Cancer of Oesophagus or Gastricus- New Assessment of Technology of Endosonography: findings. Journal of Epidemiology Community Health, 2010, 64: A36-A37. DOI:10.1136/jech.2010.120477.8.

  13. Bywater, T.; Hutchings, J.M.; Linck, P.; Whitaker, C.J.; Daley, D.M.; Yeo, S.T. & Edwards, R.T. Incredible Years parent training support for foster carers in Wales: a multi-centre feasibility study. Child: Care, Health and Development, 2010, 37 (2), 233-243. DOI: 10.1111/j.1365-2214.2010.01155.x.

  14. Tracey Bywater, Judy Hutchings, David Daley, Chris Whitaker, Seow Tien Yeo, Karen Jones, Catrin Eames, and Rhiannon Tudor Edwards. Long-term effectiveness of a parenting intervention for children at risk of developing conduct disorder. The British Journal of Psychiatry, 2009, 195, p. 318-324. DOI: 10.1192/bjp.bp.108.056531.

  15. Gill Windle, Dyfrig Hughes, Pat Linck, Ian Russell, Rhodri Morgan, Bob Woods, Vanessa Burholt, Rhiannon Tudor Edwards, Carla Reeves, Seow Tien Yeo. Public health interventions to promote mental well-being in people aged 65 and over: systematic review of effectiveness and cost-effectiveness, NICE: London., 2008.

  16. Gill Windle, Pat Linck, Rhodri Morgan, Dyfrig Hughes, Vanessa Burholt, Carla Reeves, Seow Tien Yeo, Bob Woods, Rhiannon Tudor Edwards, Ian Russell. Evidence Tables: Public health interventions to promote mental well-being in people aged 65 and over. A systematic review of effectiveness and cost effectiveness, NICE: London, 2008.

  17. Yeo, S.T. and Edwards, R.T. Encouraging fruit consumption in primary school children: a pilot study in North Wales, UK. Journal of Human Nutrition and Dietetics, 2006, 19(4), 299-302. DOI: 10.1111/j.1365-277X.2006.00706.x.

  18. Thomson, C., Beggs, I., Martin, D., McCaldin, D, Edwards, R.T., Russell, D., Yeo, S.T., Russell, I.T., Gibson, J.N.A. Executive Summary: Focus on Research: Steroid injections (methylprednisolone) in the treatment of Morton’s neuroma: patient-blind randomised trial. Scottish Executive Health Department, Chief Scientist Office: Scotland, 2006.

  19. Hughes, D.A., Tunnage, B. and Yeo, S.T. Drugs for exceptionally rare diseases: Do they deserve special status for funding? Quarterly Journal of Medicine, 2005, 98 (11): 829-836. DOI: 10.1093/qjmed/hci128.