RHiNO: Respiratory Health in Neonatal Outcomes


Medical Research Council

Collaborating Investigators/Institutions:

Cardiff and Vale University Health Board
Cardiff University
University of Bristol
University of Sheffield
University of South Wales

Project Summary

Survival of preterm infants has markedly improved with modern developments in neonatal care, however, it is recognised that these infants mat still have adverse long-term respiratory outcomes into childhood and beyond.

The RHiNO study consists of two parts:

  1. A screening of a cohort of preterm-born (< 34 weeks gestation) to identify the prevalence on reduced lung function
  2. A trial to assess if 12 week treatment with bronchodilator and/or anti-inflammatory modifies the underlying mechanisms and/or improves airway obstruction