Dr Catrin Plumpton

Catrin holds an MMath degree and an MSc in Computer Systems from the University of Wales, Bangor, and completed her PhD on classification methods for fMRI data in 2011. Catrin joined the Centre for Health Economics and Medicines Evaluation in 2010. Catrin has since worked on multiple health economic modelling projects and trial-based economic evaluations and has supervised post-graduate health economic students in the fields of orphan drugs and pharmacogenetics. Her research interests lie in the methodologies of trial-based economic evaluation and decision analytic modelling.  

Her research has led to over 30 publications including in the prestigious medical journals The Lancet and BMJ, as well as the top-ranking discipline-specific journals, Clinical Pharmacology and Therapeutics, Value in Health, and Health Economics. She is currently the alternate member (deputy) Health Economist for the New Medicines Group in Wales. 

Catrin leads and supports the health economics components of several projects aligned with her interests.  

I am willing to supervise a PhD

2022

• PublishedLinear mixed models to handle missing at random data in trial-based economic evaluations
  Gabrio, A., Plumpton, C., Banerjee, S. & Leurent, B., Jun 2022, In: Health Economics. 31, 6, p. 1276-1287 12 p.
  Research output: Contribution to journal › Article › peer-review
• PublishedSupporting People With Type 2 Diabetes in the Effective Use of Their Medicine Through Mobile Health Technology Integrated With Clinical Care to Reduce Cardiovascular Risk: Protocol for an Effectiveness and Cost-effectiveness Randomized Controlled Trial
  Farmer, A. J., Jones, L., Newhouse, N., Kenning, C., Williams, N., Chi, Y., Bartlett, K., Plumpton, C., McSharry, J., Cholerton, R., Holmes, E., Robinson, S., Allen, J., Gudgin, B., Velardo, C., Rutter, H., Horne, R., Tarassenko, L., Williams, V., Locock, L., Rea, R., Yu, L.-M., Hughes, D., Bower, P. & French, D. P., 21 Feb 2022, In: JMIR Research Protocols. 11, 2, e32918.
  Research output: Contribution to journal › Article › peer-review

2021

• PublishedLamotrigine versus levetiracetam or zonisamide for focal epilepsy and valproate versus levetiracetam for generalised and unclassified epilepsy: two SANAD II non-inferiority RCTs
  Marson, A. G., Burnside, G., Appleton, R., Smith, D., Leach, J. P., Sills, G., Tudor-Smith, C., Plumpton, C., Hughes, D., Williamson, P. R., Baker, G., Balabanova, S., Taylor, C., Brown, R., Hindley, D., Howell, S., Maguire, M., Mohanraj, R. & Smith, P. E., Dec 2021, In: Health Technology Assessment. 25, 75, 162 p.
  Research output: Contribution to journal › Article › peer-review
• PublishedThe SANAD II study of the effectiveness and cost-effectiveness of levetiracetam, zonisamide or lamotrigine for newly diagnosed focal epilepsy: an open-label, non-inferiority, multicentre, phase 4, randomised controlled trial
  Marson, A., Burnside, G., Appleton, R., Smith, D., Leach, J. P., Sills, G., Tudor-Smith, C., Plumpton, C., Hughes, D., Williamson, P., Baker, G. A., Balabanova, S., Taylor, C., Brown, R., Hindley, D., Howell, S., Maguire, M., Mohanraj, R. & Smith, P. E., 10 Apr 2021, In: The Lancet. 397, 10282, p. 1363-1374
  Research output: Contribution to journal › Article › peer-review
• PublishedThe SANAD II study of the effectiveness and cost-effectiveness of valproate versus levetiracetam for newly diagnosed generalised and unclassifiable epilepsy: an open-label, non-inferiority, multicentre, phase 4, randomised controlled trial
  Marson, A., Burnside, G., Appleton, R., Leach, J. P., Sills, G., Tudor-Smith, C., Plumpton, C., Hughes, D., Williamson, P., Baker, G. A., Balabanova, S., Taylor, C., Brown, R., Hindley, D., Howell, S., Maguire, M., Mohanraj, R. & Smith, P. E., 10 Apr 2021, In: The Lancet. 397, 10282, p. 1375-1386
  Research output: Contribution to journal › Article › peer-review

2020

• PublishedStudy protocol for a pragmatic randomised controlled trial comparing the effectiveness and cost effectiveness of levetiracetam and zonisamide versus standard treatments for epilepsy: a comparison of Standard And New Antiepileptic Drugs (SANAD-II)
  Balabanova, S., Taylor, C., Sills, G., Burnside, G., Plumpton, C., Smith, P., Appleton, R., Leach, J. P., Johnson, M., Baker, G. A., Pirmohamed, M., Hughes, D., Williamson, P., Tudor-Smith, C. & Marson, A. G., 26 Aug 2020, In: BMJ Open. 10, 8, e040635.
  Research output: Contribution to journal › Article › peer-review

2019

• PublishedAdalimumab in combination with methotrexate for refractory uveitis associated with juvenile idiopathic arthritis: a RCT
  Ramanan, A. V., Dick, A. D., Jones, A. P., Hughes, D., McKay, A., Rosala_Hanna, A., Williamson, P. R., Hardwick, B., Hickey, H., Rainford, N., Kolamunnage-Dona, R., Culeddu, G., Plumpton, C., Wood, E., Compeyrot-Lacassagne, S., Woo, P., Eldesten, C. & Beresford, M. W., 10 Apr 2019, In: Health Technology Assessment. 23, 15, p. 1-174 174 p.
  Research output: Contribution to journal › Article › peer-review
• PublishedAttitudes towards epilepsy in the UK population: Results from a 2018 national survey
  Holmes, E., Bourke, S. & Plumpton, C., Feb 2019, In: Seizure: European Journal of Epilepsy. 65, p. 12-19
  Research output: Contribution to journal › Article › peer-review
• PublishedCost-effectiveness analysis of adalimumab for the treatment of uveitis associated with Juvenile Idiopathic Arthritis
  Hughes, D. A., Culeddu, G., Plumpton, C. O., Wood, E., Dick, A. D., Jones, A. P., McKay, A., Williamson, P. R., Compeyrot Lacassagne, S., Hardwick, B., Hickey, H., Woo, P., Beresford, M. W. & Ramanan, A. V., Mar 2019, In: Ophthalmology. 126, 3, p. 415-424
  Research output: Contribution to journal › Article › peer-review
• PublishedCost-effectiveness analysis of adalimumab for the treatment of uveitis associated with Juvenile Idiopathic Arthritis: Authors’ reply.
  Hughes, D., Culeddu, G., Plumpton, C., Wood, E., Dick, A. D., Beresford, M. W. & Ramanan, A. V., Mar 2019, In: Ophthalmology. 126, 3, p. e24-e25
  Research output: Contribution to journal › Letter › peer-review
• PublishedCost-effectiveness of panel tests for multiple pharmacogenes associated with adverse drug reactions: An evaluation framework
  Plumpton, C., Pirmohamed, M. & Hughes, D., Jun 2019, In: Clinical Pharmacology and Therapeutics. 105, 6, p. 1429-1438
  Research output: Contribution to journal › Article › peer-review
• PublishedPatient-focused drug development methods for benefit-risk assessments: A case study using discrete choice experiment for antiepileptic drugs
  Holmes, E. A. F., Plumpton, C., Baker, G. A., Jacoby, A., Ring, A., Williamson, P., Marson, A. & Hughes, D. A., Mar 2019, In: Clinical Pharmacology and Therapeutics. 105, 3, p. 672-683 12 p.
  Research output: Contribution to journal › Article › peer-review

2018

• PublishedPET-PANC: multicentre prospective diagnostic accuracy and health economic analysis study of the impact of combined modality 18fluorine-2-fluoro-2-deoxy-d-glucose positron emission tomography with computed tomography scanning in the diagnosis and management of pancreatic cancer
  Ghaneh, P., Hanson, R., Titman, A., Lancaster, G., Plumpton, C., Lloyd-Williams, H., Yeo, S. T., Edwards, R., Johnson, C., Abu Hilal, M., Higginson, A., Armstrong, T., Smith, A., Scarsbrook, A., McKay, C., Carter, R., Sutcliffe, R., Bramhall, S., Kocher, H., Cunningham, D., Pereira, S., Davidson, B., Chang, D., Khan, S., Zealley, I., Sarker, D., Al Sarireh, B., Charnley, R., Lobo, D., Nicolson, M., Halloran, C., Raraty, M., Sutton, R., Vinjamuri, S., Evans, J., Campbell, F., Deeks, J., Sanghera, B., Wong, W.-L. & Neoptolemos, J., 6 Feb 2018, In: Health Technology Assessment. 22, 7, 148 p.
  Research output: Contribution to journal › Article › peer-review
• PublishedRare disease prevention and treatment: The need for a level playing field
  Hughes, D. & Plumpton, C., Feb 2018, In: Pharmacogenomics. 19, 3, p. 243-247
  Research output: Contribution to journal › Article › peer-review
• PublishedSocietal preferences for funding orphan drugs in the United Kingdom: An application of person trade off and discrete choice experiment methods
  Bourke, S. M., Plumpton, C. & Hughes, D., 9 May 2018, In: Value in Health. 21, 5, p. 538-546
  Research output: Contribution to journal › Article › peer-review

2017

• PublishedCost effectiveness analysis of HLA-B*58:01 genotyping prior to initiation of allopurinol for gout
  Plumpton, C., Alfirevic, A., Pirmohamed, M. & Hughes, D., 1 Oct 2017, In: Rheumatology. 56, 10, p. 1729-1739
  Research output: Contribution to journal › Article › peer-review
• PublishedCost-Effectiveness Of PET/CT In Pre-Operative Staging Of Pancreatic Cancer: An Economic Evaluation Of The PET-PANC Cohort Study
  Plumpton, C., Ghaneh, P., Lloyd-Williams, H., Yeo, S. T. & Edwards, R., Oct 2017, In: Value in Health. 20, 9, p. A589
  Research output: Contribution to journal › Article
• PublishedCost-effectiveness of HLA-B*15:02 screening in Malaysia
  Plumpton, C. & Hughes, D., Oct 2017, In: British Journal of Dermatology. 177, 4, p. 904-905
  Research output: Contribution to journal › Comment/debate
• PublishedCost-effectiveness of paediatric central venous catheters in the UK: A secondary publication from the CATCH clinical trial
  Ridyard, C., Plumpton, C., Gilbert, R. E. & Hughes, D., 19 Sept 2017, In: Frontiers in Pharmacology. 8, 644.
  Research output: Contribution to journal › Article › peer-review
• PublishedRenal transplant patients’ preference for the supply and delivery of immunosuppressants in Wales: A discrete choice experiment
  Hagemi, A., Plumpton, C. & Hughes, D., 2 Oct 2017, In: BMC Nephrology. 18, 305.
  Research output: Contribution to journal › Article › peer-review
• PublishedThe cancer care experiences of gay, lesbian and bisexual patients: A secondary analysis of data from the UK Cancer Patient Experience Survey.
  Hulbert-Williams, N., Plumpton, C., Flowers, P., McHugh, R., Neal, R., Semlyen, J. & Storey, L., Jul 2017, In: European Journal of Cancer Care. 26, 4, e12670.
  Research output: Contribution to journal › Article › peer-review

2016

• PublishedA systematic review of economic evaluations of pharmacogenetic testing for prevention of adverse drug reactions
  Plumpton, C. O., Roberts, D., Pirmohamed, M. & Hughes, D. A., Aug 2016, In: Pharmacoeconomics. 34, 8, p. 771-793
  Research output: Contribution to journal › Article › peer-review
• PublishedConducting Economic Evaluations Alongside Randomised Trials: Current Methodological Issues and Novel Approaches
  Hughes, D., Charles, J. M., Dawoud, D. M., Edwards, R. T., Holmes, E. A., Jones, C. L., Parham, P., Plumpton, C., Ridyard, C. O., Lloyd-Williams, H., Wood, E. M. & Yeo, S., May 2016, In: Pharmacoeconomics. 34, 5, p. 447-461
  Research output: Contribution to journal › Article › peer-review
• PublishedMultiple imputation of multiple multi-item scales when a full imputation model is infeasible
  Hughes, D., Plumpton, C. O., Morris, T., Hughes, D. A. & White, I. R., 26 Jan 2016, In: BMC Research Notes. 9, 45, p. 1-15
  Research output: Contribution to journal › Article › peer-review

2015

• PublishedAdherence of patients to long-term medication: a cross-sectional study of antihypertensive regimens in Austria
  Lotsch, F., Auer-Hackenberg, L., Groger, M., Rehman, K., Morrison, V. L., Holmes, E. A., Parveen, S., Plumpton, C. O., Clyne, W., de Geest, S., Dobbels, F., Vrijens, B., Kardas, P., Hughes, D. & Ramharter, M., May 2015, In: Wiener klinische Wochenschrift. 127, 9-10, p. 379-384
  Research output: Contribution to journal › Article › peer-review
• PublishedCost-effectiveness of screening for HLA-A*31:01 prior to initiation of carbamazepine in epilepsy
  Plumpton, C., Yip, V. L. M., Alfirevic, A., Marson, A. G., Pirmohamed, M. & Hughes, D., Apr 2015, In: Epilepsia.
  Research output: Contribution to journal › Article › peer-review
• PublishedEconomic evaluation of a behavior-modifying intervention to enhance antiepileptic drug adherence
  Hughes, D., Plumpton, C. O., Brown, I., Reuber, M., Marson, A. G. & Hughes, D. A., 26 Mar 2015, In: Epilepsy and Behavior. 45, p. 180-186
  Research output: Contribution to journal › Article › peer-review
• PublishedPharmacogenetic testing prior to carbamazepine treatment of epilepsy: 1 patients’ and physicians’ preferences for testing and service delivery
  Powell, G., Holmes, E. A., Plumpton, C. O., Ring, A., Baker, G. A., Jacoby, A., Pirmohamed, M., Marson, A. G. & Hughes, D. A., 3 Jul 2015, In: British Journal of Clinical Pharmacology. 80, 5, p. 1149-1159
  Research output: Contribution to journal › Article › peer-review
• PublishedPredictors of Self-Reported Adherence to Antihypertensive Medicines: A Multinational, Cross-Sectional Survey
  Morrison, V. L., Holmes, E. A., Parveen, S., Plumpton, C. O., Clyne, W., De Geest, S., Dobbels, F., Vrijens, B., Kardas, P. & Hughes, D., Mar 2015, In: Value in Health. 18, 2, p. 206-216
  Research output: Contribution to journal › Article › peer-review
• PublishedWhat are the experiences of cancer care in gay, lesbian and bisexual patients, and how do these differ from heterosexual cancer patients?
  Plumpton, C. O., Neal, R. D., Hulbert-Williams, N., McHugh, R., Semlyen, J., Flowers, P., Storey, L., Ream, E. & Neal, R., 28 Apr 2015, In: Psycho-Oncology. 24, S1, p. 2-3
  Research output: Contribution to journal › Article › peer-review

2014

• PublishedInvestigating preferences for support with life after stroke: a discreet choice experiment
  Holmes, E. A., Plumpton, C. O., Roberts, G. W., Burton, C. R., Farghrer, E., Plumpton, C., Roberts, G., Owen, H. & Roberts, E., 8 Feb 2014, In: BMC Health Services Research. 14, 63, p. 1-13
  Research output: Contribution to journal › Article › peer-review
• PublishedSemi-supervised ensemble update strategies for on-line classification of fMRI data
  Plumpton, C. O., 1 Feb 2014, In: Pattern Recognition Letters. 37, p. 172-177
  Research output: Contribution to journal › Article › peer-review

2013

• PublishedCost effectiveness of pharmacogenetic screening prior to initiation of carbamazepine treatment for epilepsy
  Plumpton, C. O., Yip, V., Alfirevic, A., Marson, A., Pirmohamed, M. & Hughes, D., Nov 2013, In: Value in Health. 16, 7, p. A624-A624
  Research output: Contribution to journal › Article › peer-review
• PublishedNew advice on switching antiepileptic drugs might be a false economy
  Holmes, E. A., Plumpton, C. O., Hughes, D., Holmes, E., Plumpton, C., Duerden, M., Marson, T. & Hughes, D. A., 16 Dec 2013, In: British Medical Journal. 347
  Research output: Contribution to journal › Article › peer-review

2012

• PublishedNaive random subspace ensemble with linear classifiers for real-time classification of fMRI data
  Plumpton, C. O., Kuncheva, L. I., Oosterhof, N. N. & Johnston, S. J., Jun 2012, In: Pattern Recognition. 45, 6, p. 2101-2108
  Research output: Contribution to journal › Article › peer-review

2008

• PublishedAdaptive Learning Rate for Online Linear Discriminant Classifiers
  Kuncheva, L. I. & Plumpton, C. O., 4 Dec 2008, Proceedings of the IAPR Workshop on Statistical, Structural and Syntactic Pattern Recognition (S+SSPR 2008). Orlando, Florida, USA, p. 510-519
  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

2022

• BU-IIA Funded Project: VOICES-DDH: Value of information and cost-effectiveness of screening for developmental dysplasia of the hip (DDH)

  Uncorrected DDH is associated with long-term morbidities including chronic pain and arthritis. When identified early, DDH can be treated with non-surgical interventions, believed to prevent long term limitations. Determining the optimum DDH screening strategy in terms of both clinical- and cost-effectiveness has been identified as a top ten research priority for clinical effectiveness in children’s orthopaedics in the UK, and as a research priority by a James Lind Alliance Priority Setting Partnership. Based on a value of information analysis the proposed work will identify research priority areas within the DDH pathway and also generate evidence which will be included in future research proposals in DDH. Additionally, the results will provide evidence linking costs and efficacy for service managers and industry which can aid development and implementation of new screening programmes and technologies.

  Funding awarded through the Bangor University Innovation and Impact Award (Research Wales Innovation Funding). Value = £13,331

  1 May 2022 – 30 Apr 2023

  Activity: Other (Contributor)

• Op or Non-STOP Study (Operative or Non-Surgical Treatment of Perthes' Disease)

  01/10/2023 – 15/06/2030 (Active)

• ODD SOCKS (Outcomes of Displaced Distal tibial fractures following Surgery Or Casts in Kids)

  01/11/2021 – 31/08/2027 (Active)

• The British Orthopaedic SCFE Surgery Study for Severe Stable Slips: The Big BOSS Study.

  01/11/2021 – 15/11/2027 (Active)