Professor Dyfrig Hughes
Athro mewn Ffarmacoeconomeg / Cyfarwyddwr Ymchwil
Rhagolwg
Graddiodd Dyfrig Hughes mewn fferylliaeth ym Mhrifysgol Caerdydd cyn ymgymryd â PhD mewn ffarmacoleg cardiofasgwlaidd ym Mhrifysgol Lerpwl (dan oruchwyliaeth Dr Susan Coker). Wedi hynny, hyfforddodd mewn economeg iechyd (MSc, Prifysgol Efrog), ac roedd yn aelod o'r Grŵp Ymchwil Rhagnodi ym Mhrifysgol Lerpwl (o dan gyfarwyddyd yr Athro Tom Walley) tan 2014.
Ar hyn o bryd mae Dyfrig yn Athro Ffarmacoeconomeg, yn gyd-gyfarwyddwr y Ganolfan Economeg Iechyd a Gwerthuso Meddyginiaethau ym Mhrifysgol Bangor ac yn Gyfarwyddwr Effaith ac Ymgysylltu i’r Ysgol Gwyddorau Iechyd. Mae hefyd yn arweinydd academaidd ar gyfer Fferylliaeth ym Mwrdd Iechyd Prifysgol Betsi Cadwaladr (sy'n cwmpasu Gogledd Cymru), ac mae'n athro anrhydeddus yn Adran Ffarmacoleg Foleciwlaidd a Chlinigol, Prifysgol Lerpwl.
Mae Dyfrig yn arwain y grŵp Economeg Fferyllol, Prisio ac Ymchwil Rhagnodi (PEPPER) ar weithgareddau ymchwil sy'n ymwneud â:
- Meddygaeth wedi'i bersonoli, gan gynnwys gwerthuso profion ffarmacogenetig; datblygu ac asesu ymyriadau i wella ymlyniad meddyginiaeth
- Gwerthusiad economaidd yn seiliedig ar dreialon, gan gynnwys triniaethau cyffuriau ar gyfer ffibrosis systig, uveitis sy'n gysylltiedig ag arthritis idiopathig mewn plant, diabetes math 1 a 2, epilepsi, gwaedlif postpartum a chanserau haematolegol
- Polisi fferyllol, gan gynnwys dadansoddiad o amrywiadau mewn rhagnodi, safbwyntiau cymdeithasol ar ariannu triniaethau drud ar gyfer clefydau a chanserau prin; asesiad o feddyginiaethau newydd ar gyfer GIG Cymru
- Ymchwil fethodolegol, gan gynnwys integreiddio modelu ffarmacoleg a economeg; dulliau meintiol o asesu risg-budd
Mae ei ymchwil wedi arwain at bron i 200 o gyhoeddiadau gan gynnwys yn y cyfnodolion meddygol mawreddog New England Journal of Medicine, Lancet a BMJ; yn ogystal â'r cyfnodolion disgyblaeth-benodol o'r radd flaenaf, Clinical Pharmacology and Therapeutics, Value in Health, a Health Economics. Rhestrir un o'i bapurau fel yr erthygl a ddyfynnwyd uchaf yn y British Journal of Clinical Pharmacology. Mae papurau Dyfrig wedi’u dyfynnu 9,500 o weithiau, ac yn arwain at fynegai H o 47. Yn seiliedig ar ri gyhoeddiadau diweddar, mae Dyfrig yn 2il yn y byd (1af yn y DU) am arbenigedd mewn economeg fferyllol (yn ôl Expertscape, Hydref 2019) . Mae wedi arwain a chyfrannu at ymchwil gwerth cyfanswm o £ 56.6m.
Mae Dyfrig wedi arwain gweithgareddau ffarmacoeconomaidd Canolfan Therapiwteg a Thocsicoleg Cymru Gyfan, gan gyfrannu at dros 200 o adroddiadau Asesu Technoleg Iechyd sylweddol yn llywio polisi meddyginiaethau yng Nghymru. Mae'n aelod o Grŵp Strategaeth Meddyginiaethau Cymru Gyfan, ac yn gyn-aelod o bwyllgor gwerthuso technoleg NICE. Mae'n cadeirio'r gweithgor gwerthuso profion ffarmacogenomeg ar gyfer y Rhaglen Genomeg yn GIG Lloegr a Gwella'r GIG, ac mae hefyd yn hyrwyddwr ffarmacogenetig ar gyfer y Gymdeithas Fferyllol Frenhinol. Mae Dyfrig hefyd yn gynghorydd arbenigol i Bwyllgor Cynhyrchion Meddyginiaethol Amddifad Asiantaeth Meddyginiaethau Ewrop.
Yn 2016, dyfarnwyd Dyfrig yn Uwch Arweinydd Ymchwil gan Ymchwil Iechyd a Gofal Cymru (sy'n cyfateb i Uwch Ymchwilydd NIHR). Roedd yn llywydd agoriadol (ac yn aelod anrhydeddus) y Gymdeithas Ryngwladol ar gyfer Ymlyniad Meddyginiaeth ac mae'n gymrawd etholedig o: Cymdeithas Ddysgedig Cymru, Cymdeithas Ffarmacolegol Prydain, a Chyfadran y Gymdeithas Fferyllol Frenhinol. Mae hefyd yn aelod bwrdd golygyddol o'r cyfnodolion PharmacoEconomics a Clinical Pharmacology & Therapeutics, ac yn aelod o Fwrdd Golygyddol Gweithredol y British Journal of Clinical Pharmacology a BMC Orphanet Journal of Rare Diseases.
Cyfleoedd Project PhD
Cyhoeddiadau
2024
- CyhoeddwydA model-based cost-utility analysis of an automated notification system for deteriorating patients on general wards
Holmes, E., Hughes, D. & Subbe, C., 2 Mai 2024, Yn: PLoS ONE. 19, 5, t. e0301643 e0301643.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydA proposal for using benefit-risk methods to improve the prominence of adverse event results when reporting trials
Totton, N., Waddingham, E., Owen, R., Julious, S., Hughes, D. & Cook, J., 22 Meh 2024, Yn: Trials. 25, 409.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydDeveloping an alternative care pathway for emergency ambulance responses for adults with epilepsy: A Discrete Choice Experiment to understand which configuration service users prefer. Part of the COLLABORATE project
Holmes, E., Dixon, P., Mathieson, A., Ridsdale, L., Morgan, M., McKinlay, A., Dickson, J., Goodacre, S., Jackson, M., Foster, D., Hardman, K., Bell, S., Marson, A., Hughes, D. & Noble, A. J., Ebr 2024, Yn: Seizure: European Journal of Epilepsy. 118, t. 28-37 10 t.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydDeveloping feasible person-centred care alternatives to emergency department responses for adults with epilepsy: a discrete choice analysis mixed methods study
Noble, A. J., Dixon, P., Mathieson, A., Ridsdale, L., Morgan, M., McKinlay, A., Dickson, J., Goodacre, S., Jackson, M., Morris, B., Hughes, D., Marson, T. & Holmes, E., Awst 2024, Yn: Health Services and Delivery Research (HS&DR). 12, 24
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydEconomic analysis of treatments for children who do not achieve adequate asthma control when using low-dose inhaled corticosteroids
Culeddu, G., Cividini, S., Sinha, I., Donegan, S., Maden, M., Rose, K., Fulton, O., Turner, S., Smith, C. T. & Hughes, D., 30 Gorff 2024, Yn: Disease in Childhood. 109, suppl 1
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl Cynhadledd › adolygiad gan gymheiriaid - E-gyhoeddi cyn argraffuEvidence following conditional NICE technology appraisal recommendations: A critical analysis of methods, quality and risk of bias
Pijeira Perez, Y. & Hughes, D., 9 Medi 2024, (E-gyhoeddi cyn argraffu) Yn: Pharmacoeconomics.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydPatient-led urate self-monitoring to improve clinical outcomes in people with gout: a feasibility study
Michael, T. J. F., Wright, D. F. B., Chan, J. S., Coleshill, M. J., Aslani, P., Hughes, D., Day, R. O. & Stocker, S. L., Gorff 2024, Yn: ACR Open Rheumatology. 6, 7, t. 403-411 9 t.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydService users' preferences and feasibility – which alternative care pathway for adult ambulance users achieves the optimal balance? Workshops for the COLLABORATE project
Noble, A. J., Morris, B., Dixon, P., Mathieson, A., Ridsdale, L., Morgan, M., Dickson, J., Goodacre, S., Jackson, M., Hughes, D., Marson, A. & Holmes, E., Ebr 2024, Yn: Seizure: European Journal of Epilepsy. 118, t. 17-27 11 t.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - E-gyhoeddi cyn argraffuSupporting people with type 2 diabetes in effective use of their medicine through mobile health technology integrated with clinical care (SuMMiT-D pilot): results of a feasibility randomised trial
SuMMiT-D Collaborative Group , 25 Ion 2024, (E-gyhoeddi cyn argraffu) Yn: Pilot and Feasibility Studies. 10, 1, 15.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydThe clinical and cost-effectiveness of interventions for preventing continence issues resulting from birth trauma: a rapid review
Anthony, B., Davies, J., Pisavadia, K., Roberts, S., Spencer, L. H., Gillen, E., Hounsome, J., Noyes, J., Hughes, D., Fitzsimmons, D., Edwards, R. T., Edwards, A., Cooper, A. & Lewis, R., 9 Medi 2024, MedRxiv.
Allbwn ymchwil: Papur gweithio › Rhagargraffiad - CyhoeddwydThe costs and cost-effectiveness of different service models of palliatice care, focusing on end of life care: A rapid review
Spencer, L., Anthony, B., Davies, J., Pisavadia, K., Gillen, E., Noyes, J., Fitzsimmons, D., Lewis, R., Cooper, A., Hughes, D., Edwards, R. T. & Edwards, A., 7 Maw 2024, MedRxiv, 118 t.
Allbwn ymchwil: Papur gweithio › Rhagargraffiad - CyhoeddwydThe experiences and perspectives of people with gout on urate self-monitoring
Michael, T. J. F., Chan, J. S., Hughes, S., Wright, D. F. B., Coleshill, M. J., Hughes, D., Day, R. O., Aslani, P. & Stocker, S. L., Meh 2024, Yn: Health Expectations. 27, 3, 9 t., e14071.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydWe need to talk about values: a proposed framework for the articulation of normative reasoning in health technology assessment
Charlton, V., diStefano, M., Mitchell, P., Morrell, L., Rand, L., Badano, G., Baker, R., Calnan, M., Chalkidou, K., Culyer, A., Howden, D., Hughes, D., Lomas, J., Max, C., McCabe, C., O'Mahony, J. F., Paulden, M., Pemberton-Whiteley, Z., Rid, A., Scuffham, P., Sculpher, M., Shah, K., Weale, A. & Wester, G., Ebr 2024, Yn: Health Economics, Policy and Law. 19, 2, t. 153-173
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
2023
- CyhoeddwydA framework for understanding sources of bias in medication adherence research
Sinnappah, K. A., Hughes, D., Stocker, S. L., Vrijens, B., Aronson, J. K. & Wright, D. F. B., Tach 2023, Yn: British Journal of Clinical Pharmacology. 89, 11, t. 3444-3453
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydA “Bundle of Care” to Improve Anticoagulation Control in Patients Receiving Warfarin in Uganda and South Africa: Protocol for an Implementation Study
Jorgensen, A., Waitt, C., Orrell, C., Cheng-Hock, T., Sekaggya-Wiltshire, C., Hughes, D., Allen, E., Okello, E., Tatz, G., Culeddu, G., Asiimwe, I. G., Semakula, J. R., Mouton, J. P., Cohen, K., Blockman, M., Lamorde, M. & Pirmohamed, M., 19 Gorff 2023, Yn: Journal of Medical Internet Research. 12, e46710.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydAppropriate design and reporting of superiority, equivalence and non-inferiority clinical trials incorporating a benefit risk assessment: the BRAINS study including expert workshop
Totton, N., Julious, S., Coates, E., Hughes, D., Cook, J., Biggs, K., Hewitt, C., Day, S. & Cooke, A., Hyd 2023, Yn: Health Technology Assessment. 27, 20, 86 t.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydBest step-up treatments for children with uncontrolled asthma: A systematic review and network meta-analysis of individual participant data
Cividini, S., Sinha, I., Donegan, S., Maden, M., Rose, K., Fulton, O., Culeddu, G., Hughes, D., Turner, S. & Tudor-Smith, C., 21 Rhag 2023, Yn: European Respiratory Journal. 62, 6, 2301011.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydBetween- and within-individual sociodemographic and psychological determinants of PrEP adherence among men who have sex with men prescribed a daily PrEP regimen in Wales
Gillespie, D., de Bruin, M., Hughes, D., Ma, R., Williams, A., Wood, F., Couzens, Z., Jones, A. T. & Hood, K., Mai 2023, Yn: AIDS and Behavior. 27, 5, t. 1564-1572 9 t.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydChanging Agendas on Sleep, Treatment and Learning in Epilepsy (CASTLE) Sleep-E: A protocol for a randomised controlled trial comparing an online behavioural sleep intervention with standard care in children with Rolandic epilepsy
Al-Najjar, N., Bray, L., Carter, B., Collingwood, A., Cook, G., Crudgington, H., Dietz, K., Hardy, W., Hiscock, H., Hughes, D., Morris, C., Rouncefield-Swales , A., Saron, H., Spowart, C., Stibbs-Easton, L., Tudur Smith, C., Watson, V., Whittle, L., Wiggs, L., Wood, E., Gringas, P. & Pal, D. K., 10 Maw 2023, Yn: BMJ Open. 13, 3, e065769.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydCost effectiveness analysis of treatments for children with uncontrolled asthma symptoms despite taking inhaled corticosteroids
Culeddu, G., Sinha, I., Donegan, S., Maden, M., Cividini, S., Rose, K., Fulton, O., Turner, S., Tudor-Smith, C. & Hughes, D., 27 Hyd 2023, Yn: European Respiratory Journal. 62 , Supplement 67, PA 523.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Crynodeb Cyfarfod › adolygiad gan gymheiriaid - CyhoeddwydCosts of orphan medicinal products: longitudinal analysis of expenditure in Wales
Pijeira Perez, Y., Wood, E. & Hughes, D., 1 Tach 2023, Yn: Orphanet Journal of Rare Diseases. 18, 1, 342.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydEffectiveness of out-patient based acute heart failure care: A pilot randomised controlled trial
Wong, K. Y. K., Hughes, D., Debski, M., Latt, N., Assaf, O., Abdelrahman, A., Taylor, R., Allgar, V., McNeill, L., Howard, S., Wong, S. Y. S., Jones, R., Cassidy, C. J., Seed, A., Galasko, G., Clark, A., Davis, G. K., Montasem, A., Lang, C. C., Kalra, P. R., Campbell, R., Lip, G. Y. H. & Cleland, J. G. F., Hyd 2023, Yn: Acta Cardiologica. 78, 7, t. 828-837 10 t.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydHealth utilities and quality-adjusted life years for patients with amyotrophic lateral sclerosis receiving reldesemtiv or placebo in FORTITUDE-ALS
Gebrehiwet, P., Meng, L., Saroccoa, P., Wei, J., Wolff, A. A., Butzner, M., Chio, A., Andrews, J. A., Genge, A., Hughes, D., Jackson, C. E., Lechtzin, N., Miller, T. M. & Shefner, J. M., 31 Maw 2023, Yn: Journal of Medical Economics. 26, 1, t. 488-493 6 t.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydMedication adherence research comes of age
Wright, D. F. B., Sinnappah, K. A. & Hughes, D., Gorff 2023, Yn: British Journal of Clinical Pharmacology. 89, 7, t. 1914-1917
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Golygyddiad › adolygiad gan gymheiriaid - CyhoeddwydMethodological considerations on estimating medication adherence from self-report, electronic monitoring, and electronic healthcare databases using the TEOS framework
Dima, A. L., Allemann, S. S., Dunbar-Jacob, J., Hughes, D., Vrijens, B. & Wilson, I., Gorff 2023, Yn: British Journal of Clinical Pharmacology. 89, 7, t. 1918-1927
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydPsychometric properties of an adapted stigma scale and experiences of stigma associated with HIV pre-exposure prophylaxis use among men who have sex with men: a mixed methods study
Gillespie, D. & Hughes, D., Gorff 2023, Yn: AIDS and Behavior. 27, 7, t. 2397-2410 14 t.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydSuperiority and cost-effectiveness of monthly extended-release buprenorphine versus daily standard of care medication: a pragmatic, parallel-group, open-label, multicentre, randomised, controlled, phase 3 trial
Marsden, J., Kelleher, M., Gilvarry, E., Mitcheson, L., Bisla, J., Cape, A., Cowden, F., Day, E., Dewhurst, J., Evans, R., Hardy, W., Hearn, A., Kelly, J., Lowry, N., McCusker, M., Murphy, C., Murray, R., Myton, T., Quarshie, S., Vanderwaal, R., Wareham, A., Hughes, D. & Hoare, Z., Rhag 2023, Yn: eClinicalMedicine. 66, 23 t., 102331.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydThe impact of parent treatment preference and other factors on recruitment: lessons learned from a paediatric epilepsy randomised controlled trial
Carter, B., Bray, L., Al-Najjar, N., Tort Piella, A., Smith, C. T., Spowart, C., Collingwood, A., Crudgington, H., Currier, J., Hughes, D., Wood, E., Martin, R., Morris, C., Roberts, D., Rouncefield-Swales , A., Sutherland, H., Watson, V., Cook, G., Wiggs, L., Gringas, P. & Pal, D., 6 Chwef 2023, Yn: Trials. 24, 1, 83.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydValue of improving patient safety: Health-economic considerations for Rapid Response Systems – a Rapid Review of the Literature and Expert Round Table
Subbe, C., Hughes, D., Lewis, S., Holmes, E., Kalkman, C. J., So, R. K., Tranka, S. & Welch, J., 17 Ebr 2023, Yn: BMJ Open. 13, 4, e065819.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydWhat interventions or best practice are there to support people with Long COVID, or similar post-viral conditions or conditions characterised by fatigue, to return to normal activities: a rapid review
Spencer, L., Hendry, A., Makanjuola, A., Anthony, B., Davies, J., Pisavadia, K., Hughes, D., Fitzsimmons, D., Wilkinson, C., Edwards, R. T., Lewis, R., Cooper, A. & Edwards, A., 28 Ion 2023, 34 t. (MedRxiv).
Allbwn ymchwil: Papur gweithio › Rhagargraffiad - CyhoeddwydWhat is the effectiveness and cost-effectiveness of interventions in reducing the harms for children and young people who have been exposed to domestic violence or abuse: a rapid review.
Spencer, L., Hendry, A., Makanjuola, A., Pisavadia, K., Davies, J., Albustami, M., Anthony, B., Wilkinson, C., Fitzsimmons, D., Hughes, D., Edwards, R. T., Lewis, R., Cooper, A. & Edwards, A., 10 Mai 2023, 79 t.
Allbwn ymchwil: Llyfr/Adroddiad › Adroddiad Comisiwn
2022
- CyhoeddwydAdvanced therapy medicinal products: a comprehensive overview for pharmacy professionals
McKenzie, C. A., Chappel, J., Guy, R. H., Hawksworth, G., Hughes, D. & Black, A., 12 Awst 2022, Yn: Pharmaceutical Journal.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydAdverse drug reactions, multimorbidity and polypharmacy: A prospective analysis of one month of medical admissions
Osanlou, R., Walker, L., Hughes, D., Burnside, G. & Pirmohamed, M., 4 Gorff 2022, Yn: BMJ Open. 12, 7, e055551.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydChoice of oral anticoagulant prescribed by general practices in Wales: Application of Dirichlet regression and linked data
Hill-McManus, D. & Hughes, D., Meh 2022, Yn: British Journal of Clinical Pharmacology. 88, 6, t. 2782-2792 11 t.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydClinical interventions to improve adherence to urate-lowering therapy in patients with gout: a systematic review
Sinnappah, K. A., Stocker, S. L., Chan, J. S., Hughes, D. A. & Wright, D. F. B., 25 Meh 2022, Yn: International Journal of Pharmacy Practice. 30, 3, t. 215-225 11 t.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydExperiences of men who have sex with men when initiating, implementing, and persisting with HIV pre-exposure prophylaxis
Gillespie, D., Wood, F., Williams, A., Ma, R., de Bruin, M., Hughes, D., Jones, A. T., Couzens, Z. & Hood, K., Awst 2022, Yn: Health Expectations. 25, 4, t. 1332-1341 10 t.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydExtended-release pharmacotherapy for opioid use disorder (EXPO): protocol for an open-label randomised controlled trial of the effectiveness and cost-effectiveness of injectable buprenorphine versus sublingual tablet buprenorphine and oral liquid methadone
Marsden, J., Kelleher, M., Hoare, Z., Hughes, D., Bisla, J., Cape, A., Cowden, F., Day, E., Dewhurst, J., Evans, R., Hearn, A., Kelly, J., Lowry, N., McCusker, M., Murphy, C., Murray, R., Myton, T., Quarshie, S., Scott, G., Turner, S., Vanderwaal, R., Wareham, A., Gilvarry, E. & Mitcheson, L., 19 Awst 2022, Yn: Trials. 23, 1, 697.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydHealth utilities and costs for neuromyelitis optica spectrum disorder
Hughes, D., Bourke, S., Jones, A., Bhatt, R., Huda, S., Mutch, K. & Jacob, A., 2022, Yn: Orphanet Journal of Rare Diseases. 17, 11 t., 159.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydMethods for Extrapolating Survival Analyses for the Economic Evaluation of Advanced Therapy Medicinal Products
Hardy, W. & Hughes, D., 16 Medi 2022, Yn: Human Gene Therapy. 33, 17-18, t. 845-856
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydNovel oral iron therapy for iron deficiency anaemia: How to value safety in a new drug?
Culeddu, G., Su, L., Chen, Y., Pereira, D. I. A., Powell, J. J. & Hughes, D., Maw 2022, Yn: British Journal of Clinical Pharmacology. 88, 3, t. 1347-1357 11 t.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydPrEP use, sexual behaviour, and PrEP adherence among men who have sex with men living in Wales prior to and during the COVID-19 pandemic
Gillespie, D., Couzens, Z., de Bruin, M., Hughes, D., Jones, A., Ma, R., Williams, A., Wood, F. & Blee, K., Awst 2022, Yn: AIDS and Behavior. 26, 8, t. 2746-2757 12 t.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydRES00019. Wales COVID-19 Evidence Centre. A rapid evidence summary indicating the evidence of the inverse care law in social care in Wales and has this been exacerbated by the COVID-19 pandemic?
Spencer, L., Hendry, A., Makanjuola, A., Hughes, D., Wilkinson, C., Pisavadia, K., Davies, J., Fitzsimmons, D. & Edwards, R. T., Chwef 2022, Welsh Government. 33 t.
Allbwn ymchwil: Llyfr/Adroddiad › Adoddiad Arall - CyhoeddwydRES00038. Wales COVID-19 Evidence Centre. A rapid evidence summary of the cost impact of Long COVID on employment and caring responsibilities
Spencer, L., Hendry, A., Davies, J., Pisavadia, K., Hughes, D. & Edwards, R. T., Mai 2022, Welsh Government. 18 t.
Allbwn ymchwil: Llyfr/Adroddiad › Adoddiad Arall - CyhoeddwydSupply-side cost-effectiveness thresholds: questions for evidence-based policy
Sampson, C., Zamora, B., Watson, S., Cairns, J., Chalkidou, K., Cubi-Molla, P., Devlin, N., García-Lorenzo, B., Hughes, D., Leech, A. & Towse, A., Medi 2022, Yn: Applied Health Economics and Health Policy. 20, 5, t. 651-667
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydSupporting People With Type 2 Diabetes in the Effective Use of Their Medicine Through Mobile Health Technology Integrated With Clinical Care to Reduce Cardiovascular Risk: Protocol for an Effectiveness and Cost-effectiveness Randomized Controlled Trial
Farmer, A. J., Jones, L., Newhouse, N., Kenning, C., Williams, N., Chi, Y., Bartlett, K., Plumpton, C., McSharry, J., Cholerton, R., Holmes, E., Robinson, S., Allen, J., Gudgin, B., Velardo, C., Rutter, H., Horne, R., Tarassenko, L., Williams, V., Locock, L., Rea, R., Yu, L.-M., Hughes, D., Bower, P. & French, D. P., 21 Chwef 2022, Yn: JMIR Research Protocols. 11, 2, e32918.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydWhat innovations can address inequalities experienced by women and girls due to the COVID-19 pandemic across the different areas of life/domains: work, health, living standards, personal security, participation and education? Report number – RR00027 (January 2022). Gender Inequalities: COVID-19 initiatives
Spencer, L., Hartfiel, N., Hendry, A., Anthony, B., Makanjuola, A., Pisavadia, K., Davies, J., Bray, N., Hughes, D., Wilkinson, C., Fitzsimmons, D. & Edwards, R. T., 15 Ion 2022, Health and Care Research Wales.
Allbwn ymchwil: Llyfr/Adroddiad › Adroddiad Comisiwn › adolygiad gan gymheiriaid - CyhoeddwydWhat is the long-term impact of COVID-19 on the Health-Related Quality of Life of individuals with mild symptoms (or non-hospitalised): A rapid review
Spencer, L., Hendry, A., Makanjuola, A., Davies, J., Pisavadia, K., Hughes, D., Fitzsimmons, D., Wilkinson, C., Edwards, R. T., Lewis, R., Cooper, A. & Edwards, A., 9 Medi 2022, Health and Care Research Wales, 47 t.
Allbwn ymchwil: Papur gweithio › Rhagargraffiad
2021
- CyhoeddwydA Literature Review of GP Knowledge and Understanding of ME/CFS: A Report from the Socioeconomics Working Group of the European Network on ME/CFS (EUROMENE)
Pheby, D. F. H., Araja, D., Berkis, U., Brenna, E., Cullinan, J., de Korwin, J.-D., Gitto, L., Hughes, D., Hunter, R. M., Trépel, D. & Wang-Steverding, X., Ion 2021, Yn: Medicina. 57, 1, 17 t., 7.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydA Systematic Review of Economic Evaluations of Advanced Therapy Medicinal Products
Lloyd Williams, H. & Hughes, D., Meh 2021, Yn: British Journal of Clinical Pharmacology. 87, 6, t. 2428-2443 16 t.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl adolygu › adolygiad gan gymheiriaid - CyhoeddwydAcceptability of generic versus innovator oral medicines: not only a matter of taste
Tuleu, C., Hughes, D., Clapham, D., Vallet, T. & Ruiz, F., Chwef 2021, Yn: Drug Discovery Today. 26, 2, t. 329-343
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydCombining model-based clinical trial simulation, pharmacoeconomics and value of information to optimize trial design
Hill-McManus, D. & Hughes, D., Ion 2021, Yn: CPT: Pharmacometrics & Systems Pharmacology . 10, 1, t. 75-83 9 t.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydContent of Health Economics Analysis Plans (HEAPs) for trial-based economic evaluations: expert Delphi consensus survey
Thorn, J., Davies, C. F., Brookes, S., Noble, S., Dritsaki, M., Gray, E., Hughes, D., Mihaylova, B., Petrou, S., Ridyard, C., Sach, T., Wilson, E., Wordsworth, S. & Hollingworth, W., 1 Ebr 2021, Yn: Value in Health. 24, 4, t. 539-547 9 t.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydCost-Effectiveness Analysis of Mycophenolate Mofetil Versus Cyclophosphamide for Remission Induction in Childhood Polyarteritis Nodosa
Culeddu, G., Brogan, P. A. & Hughes, D., 2021.
Allbwn ymchwil: Cyfraniad at gynhadledd › Arall › adolygiad gan gymheiriaid - CyhoeddwydCost-effectiveness of home versus hospital management of children at onset of Type 1 Diabetes: The DECIDE randomised controlled trial
McCarroll, Z., Townson, J., Pickles, T., Gregory, J. W., Playle, R., Robling, M. & Hughes, D., 19 Mai 2021, Yn: BMJ Open. 11, 5, e043523.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydEarly impact of COVID-19 social distancing measures on reported sexual behaviour of HIV pre-exposure prophylaxis users in Wales
Gillespie, D., Knapper, C., Hughes, D., Couzen, Z., Wood, F., de Bruin, M., Ma, R., Jones, A. T., Williams, A. & Hood, K., 17 Chwef 2021, Yn: Sexually transmitted infections. 97, 2, t. 85-87 3 t., 054598.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydEstablishINg the best STEp-up treatments for children with uncontrolled asthma despite INhaled corticosteroids (EINSTEIN): Protocol for a systematic review, network meta-analysis and cost-effectiveness analysis using individual participant data (IPD)
Cividini, S., Sinha, I., Donegan, S., Maden, M., Culeddu, G., Rose, K., Fulton, O., Hughes, D., Turner, S. & Smith, C. T., 5 Chwef 2021, Yn: BMJ Open. 11, e040528.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydHave infection control and prevention measures resulted in any adverse outcomes for care home and domiciliary care residents and staff? Report number: RR_00018 (November 2021)
Spencer, L., Hartfiel, N., Hendry, A., Anthony, B., Makanjuola, A., Bray, N., Hughes, D., Wilkinson, C., Fitzsimmons, D. & Edwards, R. T., 1 Tach 2021, 36 t.
Allbwn ymchwil: Llyfr/Adroddiad › Adoddiad Arall › adolygiad gan gymheiriaid - CyhoeddwydIs there a role for Natural Desiccated Thyroid in the treatment of levothyroxine unresponsive hypothyroidism? Results from a Consecutive Case Series
Heald, A., Premawardhana, L., Taylor, P., Okosieme, O., Bangi, T., Devine, H., Livingston, M., Javed, A., Moreno, G. Y. C., Watt, T., Stedman, M. & Hughes, D., 28 Rhag 2021, Yn: International Journal of Clinical Practice. 75, 12, e14967.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydLamotrigine versus levetiracetam or zonisamide for focal epilepsy and valproate versus levetiracetam for generalised and unclassified epilepsy: two SANAD II non-inferiority RCTs
Marson, A. G., Burnside, G., Appleton, R., Smith, D., Leach, J. P., Sills, G., Tudor-Smith, C., Plumpton, C., Hughes, D., Williamson, P. R., Baker, G., Balabanova, S., Taylor, C., Brown, R., Hindley, D., Howell, S., Maguire, M., Mohanraj, R. & Smith, P. E., Rhag 2021, Yn: Health Technology Assessment. 25, 75, 162 t.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydLinked Pharmacometric-Pharmacoeconomic Modeling and Simulation in Clinical Drug Development
Hill-McManus, D., Marshall, S., Liu, J., Willke, R. & Hughes, D., Gorff 2021, Yn: Clinical Pharmacology and Therapeutics. 110, 1, t. 49-63
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydLiothyronine for hypothyroidism: A candidate for disinvestment or in need of further research? A value of information analysis
Hughes, D., Skiadas, K., Fitzsimmons, D., Anderson, P. & Heald, A., 3 Rhag 2021, Yn: BMJ Open. 11, 12, e051702.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydManaging Access to Advanced Therapy Medicinal Products: Challenges for NHS Wales
Champion, A. R., Lewis, S., Davies, S. & Hughes, D., Meh 2021, Yn: British Journal of Clinical Pharmacology. 87, 6, t. 2444-2449
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydMechanistically informed non-invasive peripheral nerve stimulation for peripheral neuropathic pain: a randomised double-blind sham-controlled trial
Johnson, S., Marshall, A., Hughes, D., Holmes, E., Henrich, F., Nurmikko, T., Sharma, M., Frank, B., Bassett, P., Marshall, A. & Goebel, A., 6 Tach 2021, Yn: Journal of Translational Medicine. 19, 1, 458.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydMicrodiscectomy compared with transforaminal epidural steroid injection for persistent radicular pain caused by prolapsed intervertebral disc: the NERVES RCT
Wilby, M. J., Best, A., Wood, E., Burnside, G., Bedson, E., Short, H., Wheatley, D., Hill-McManus, D., Sharma, M., Clark, S., Bostock, J., Hay, S., Baranidharan, G., Price, C., Mannion, R., Hutchinson, P. J., Hughes, D., Marson, A. & Williamson, P. R., Ebr 2021, Yn: Health Technology Assessment. 25, 24, 86 t.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydMycophenolate Mofetil Versus Cyclophosphamide for Remission Induction in Childhood Polyarteritis Nodosa: An Open-Label, Randomized, Bayesian Noninferiority Trial
Brogan, P. A., Arch, B., Hickey, H., Anton, J., Iglesias, E., Baildam, E., Mahmood, K., Cleary, G., Moraitis, E., Papadopoulou, C., Beresford, M. W., Riley, P., Demir, S., Ozen, S., Culeddu, G., Hughes, D., Dolezalova, P., Hampson, L., Whitehead, J., Jayne, D., Ruperto, N., Tudor-Smith, C. & Eleftheriou, D., Medi 2021, Yn: Arthritis and Rheumatology. 73, 9, t. 1673-1682
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydPerceptions of European ME/CFS experts concerning knowledge and understanding of ME/CFS among primary care physicians in Europe: A report from the European ME/CFS Research Network (EUROMENE)
Cullinan, J., Pheby, D. F. H., Araja, D., Berkis, U., Brenna, E., de Korwin, J.-D., Gitto, L., Hughes, D., Hunter, R. M., Trépel, D. & Wang-Steverding, X., 26 Chwef 2021, Yn: Medicina. 57, 3, 208.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydPharmacogenomics spotlight commentary: From the United Kingdom to global populations
Magavern, E. F., Daly, A. K., Gilchrist, A. & Hughes, D., Rhag 2021, Yn: British Journal of Clinical Pharmacology. 87, 12, t. 4546-4548 3 t., 14917.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Sylw/Dadl › adolygiad gan gymheiriaid - CyhoeddwydPlasma Methylmalonic Acid Concentration in Folic Acid–Supplemented Depressed Patients with Low or Marginal Vitamin B-12: A Randomized Trial
Carter, B., Zenasni, Z., Moat, S. J., Hudson, P. R., Russell, I. T., McCaddon, A., Whitaker, R., Pink, J., Roberts, S., Wilkinson, C., Hughes, D., Betson, E., Carr, D., Jorgenson, A., Pirmohamed, M., Williams, N., Lewis, H., Lloyd, K., Sylvesture, Y. & Tranter, R., Rhag 2021, Yn: Journal of Nutrition. 151, 12, t. 3738-3745 8 t.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydQuantitative evidence synthesis methods for the assessment of the effectiveness of treatment sequences for clinical and economic decision-making: a review and taxonomy of simplifying assumptions
Lewis, R., Hughes, D., Sutton, A. & Wilkinson, C., Ion 2021, Yn: PharmacoEconomics. 39, 1, t. 25-61 37 t.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydSurgical microdiscectomy versus transforaminal epidural steroid injection in patients with sciatica secondary to herniated lumbar disc (NERVES): a phase 3, multicentre, open-label, randomised controlled trial and economic evaluation
Wilby, M. J., Best, A., Wood, E., Burnside, G., Bedson, E., Short, H., Wheatley, D., Hill-McManus, D., Sharma, M., Clark, S., Baranidharan, G., Price, C., Mannion, R., Hutchinson , P. J., Hughes, D., Marson, A. G. & Williamson, P., 1 Mai 2021, Yn: The Lancet Rheumatology. 3, 5, t. e347-e356
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydTEOS: A framework for constructing operational definitions of medication adherence based on Timelines – Events – Objectives – Sources
Dima, A. L., Allemann, S. S., Dunbar-Jacobs, J., Hughes, D., Vrijens, B. & Wilson, I., Meh 2021, Yn: British Journal of Clinical Pharmacology. 87, 6, t. 2521-2533
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydThe SANAD II study of the effectiveness and cost-effectiveness of levetiracetam, zonisamide or lamotrigine for newly diagnosed focal epilepsy: an open-label, non-inferiority, multicentre, phase 4, randomised controlled trial
Marson, A., Burnside, G., Appleton, R., Smith, D., Leach, J. P., Sills, G., Tudor-Smith, C., Plumpton, C., Hughes, D., Williamson, P., Baker, G. A., Balabanova, S., Taylor, C., Brown, R., Hindley, D., Howell, S., Maguire, M., Mohanraj, R. & Smith, P. E., 10 Ebr 2021, Yn: The Lancet. 397, 10282, t. 1363-1374
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydThe SANAD II study of the effectiveness and cost-effectiveness of valproate versus levetiracetam for newly diagnosed generalised and unclassifiable epilepsy: an open-label, non-inferiority, multicentre, phase 4, randomised controlled trial
Marson, A., Burnside, G., Appleton, R., Leach, J. P., Sills, G., Tudor-Smith, C., Plumpton, C., Hughes, D., Williamson, P., Baker, G. A., Balabanova, S., Taylor, C., Brown, R., Hindley, D., Howell, S., Maguire, M., Mohanraj, R. & Smith, P. E., 10 Ebr 2021, Yn: The Lancet. 397, 10282, t. 1375-1386
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydThe role of prevention in reducing the economic impact of ME/CFS in Europe: A report from the socioeconomics working group of the European Network on ME/CFS (EUROMENE).
Pheby, D. F. H., Araja, D., Berkis, U., Brenna, E., Cullinan, J., de Korwin, J.-D., Gitto, L., Hughes, D., Hunter, R. M., Trépel, D. & Wang-Steverding, X., 16 Ebr 2021, Yn: Medicina. 57, 4, 388.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydUsing Routinely Recorded Data in a UK RCT: A Comparison to Standard Prospective Data Collection Methods
Powell, G., Bonnett, L., Tudor-Smith, C., Hughes, D., Williamson, P. R. & Marson, A. G., 5 Gorff 2021, Yn: Trials. 22, 1, 429.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydUtilising Benefit-Risk Assessments within Clinical Trials – A Protocol for the BRAINS project
Totton, N., Julious, S., Hughes, D., Cook, J., Biggs, K., Coates, L., Cook, A., Hewitt, C. & Day, S., 19 Ion 2021, Yn: Trials. 22, 68.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydWhat should patients do if they miss a dose? A systematic review of patient information leaflets and summaries of product characteristics
Albassam, A. & Hughes, D., Chwef 2021, Yn: European Journal of Clinical Pharmacology. 77, 2, t. 251-260 10 t.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
2020
- CyhoeddwydAcute chloroquine poisoning: A comprehensive experimental toxicology assessment of the role of diazepam
Hughes, D., Tach 2020, Yn: British Journal of Pharmacology. 177, 21, t. 4975-4989 15 t.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydCarer administration of as-needed sub-cutaneous medication for breakthrough symptoms in people dying at home: the CARiAD feasibility RCT
Poolman, M., Roberts, J., Wright, S., Hendry, A., Goulden, N., Holmes, E., Byrne, A., Perkins, P., Hoare, Z., Nelson, A., Hiscock, J., Hughes, D., O'Connor, J., Foster, B., Reymond, L., Healy, S., Lewis, P., Wee, B., Johnstone, R. P., Roberts, R., Parkinson, A., Roberts, S. & Wilkinson, C., 2 Meh 2020, Yn: Health Technology Assessment. 24, 25, 150 t.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydImpact of relaxing Covid-19 social distancing measures on rural North Wales: a simulation analysis
Hughes, R. P. & Hughes, D., 14 Rhag 2020, Yn: Frontiers in Public Health. 8, 562473.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydManagement of Patients Symptomatically Unresponsive to Levothyroxine: Natural Desiccated Thyroid Extract or the Combination of Levothyroxine and Liothyronine? A Research Priority
Hughes, D., Livingston, M. & Heald, A., Medi 2020, Yn: Experimental and Clinical Endocrinology & Diabetes . 128, 9, t. 596-598
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Llythyr › adolygiad gan gymheiriaid - CyhoeddwydMedication adherence – key considerations for clinical pharmacologists
Hughes, D., Ebr 2020, Yn: British Journal of Clinical Pharmacology. 86, 4, t. 628-629 2 t.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Golygyddiad › adolygiad gan gymheiriaid - CyhoeddwydSeizure First Aid Training For people with Epilepsy (SAFE) frequently attending emergency departments and their significant others: results of a UK multi-centre randomised controlled pilot trial
Noble, A. J., Snape, D., Nevitt, S., Holmes, E., Morgan, M., Smith, C. T., Hughes, D., Buchanan, M., McVicar, J., MacCallum, E., Goodacre, S., Rinsdale, L. & Marson, A. G., 16 Ebr 2020, Yn: BMJ Open. 10, 4, e035516.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydSilver-impregnated, antibiotic-impregnated or non-impregnated ventriculoperitoneal shunts to prevent shunt infection: the BASICS three-arm RCT
Mallucci, C. L., Jenkinson, M., Conroy, E. J., Hartley, J. C., Brown, M., Moitt, T., Dalton, J., Kearns, T., Griffiths, M. J., Culeddu, G., Solomon, T., Hughes, D. & Gamble, C., 2 Ebr 2020, Yn: Health Technology Assessment. 24, 17, 114 t.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydStudy protocol for a pragmatic randomised controlled trial comparing the effectiveness and cost effectiveness of levetiracetam and zonisamide versus standard treatments for epilepsy: a comparison of Standard And New Antiepileptic Drugs (SANAD-II)
Balabanova, S., Taylor, C., Sills, G., Burnside, G., Plumpton, C., Smith, P., Appleton, R., Leach, J. P., Johnson, M., Baker, G. A., Pirmohamed, M., Hughes, D., Williamson, P., Tudor-Smith, C. & Marson, A. G., 26 Awst 2020, Yn: BMJ Open. 10, 8, e040635.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydThe Development of a Consistent Europe-Wide Approach to Investigating the Economic Impact of Myalgic Encephalomyelitis (ME/CFS): A Report from the European Network on ME/CFS (EUROMENE)
Pheby, D. F. H., Araja, D., Berkis, U., Brenna, E., Cullinan, J., de Korwin, J.-D., Gitto, L., Hughes, D., Hunter, R. M., Trépel, D. & Wang-Steverding, X., 7 Ebr 2020, Yn: Healthcare. 8, 2, 88.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydThe new and non-transparent Cancer Drugs Fund
Wood, E. & Hughes, D., Ion 2020, Yn: PharmacoEconomics. 38, 1, t. 1-4
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
2019
- CyhoeddwydA Fully Integrated Real-Time Detection, Diagnosis, and Control of Community Diarrheal Disease Clusters and Outbreaks (the INTEGRATE Project): Protocol for an Enhanced Surveillance System
McIntyre, K. M., Bolton, F. J., Christley, R. M., Cleary, P., Deja, E., Durie, A. E., Diggle, P. J., Hughes, D., de Lusignan, S., Orton, L., Radford, A. D., Elliot, A., Smith, G. E., Snape, D. A., Stanistreet, D., Vivancos, R., Winstanley, C. & O'Brien, S. J., 26 Medi 2019, Yn: JMIR Research Protocols. 8, 9, t. e13941 10 t., e13941.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydAdalimumab in combination with methotrexate for refractory uveitis associated with juvenile idiopathic arthritis: a RCT
Ramanan, A. V., Dick, A. D., Jones, A. P., Hughes, D., McKay, A., Rosala_Hanna, A., Williamson, P. R., Hardwick, B., Hickey, H., Rainford, N., Kolamunnage-Dona, R., Culeddu, G., Plumpton, C., Wood, E., Compeyrot-Lacassagne, S., Woo, P., Eldesten, C. & Beresford, M. W., 10 Ebr 2019, Yn: Health Technology Assessment. 23, 15, t. 1-174 174 t.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydAntibiotic or silver versus standard ventriculoperitoneal shunts (BASICS): a multi-centre, single-blinded, randomised trial and economic evaluation
Mallucci, C. L., Jenkinson, M. D., Conroy, E. J., Hartley, J. C., Brown, M., Dalton, J., Kearns, T., Moitt, T., Griffiths, M. J., Culeddu, G., Solomon, T., Hughes, D. & Gamble, C., 26 Hyd 2019, Yn: The Lancet. 394, 10208, t. 1530-1539 10 t.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydCARer-ADministration of as-needed subcutaneous medication for breakthrough symptoms in homebased dying patients (CARiAD): study protocol for a UK-based open randomised pilot trial
Poolman, M., Roberts, J., Byrne, A., Perkins, P., Hoare, Z., Nelson, A., Hiscock, J., Hughes, D., Foster, B., O'Connor, J., Reymond, L., Healy, S., Roberts, R., Wee, B., Lewis, P., Johnstone, R., Roberts, S., Holmes, E., Wright, S., Hendry, A. & Wilkinson, C., 7 Chwef 2019, Yn: Trials. 20, 1, 16 t., 105.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydChallenges for economic evaluation of strategies to contain antimicrobial resistance
Holmes, E. & Hughes, D., 27 Medi 2019, Yn: Antibiotics. 8, 4, 8 t., 166.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Sylw/Dadl › adolygiad gan gymheiriaid - CyhoeddwydCommunity views on factors affecting medicines resource allocation: Cross-sectional survey of 3080 adults in Australia
Chim, L., Salkeld, G., Kelly, P., Lipworth, W., Hughes, D. & Stockler, M., 2019, Yn: Australian Health Review . 43, 3, t. 254-260
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydContinuous subcutaneous insulin infusion versus multiple daily injection regimens in children and young people at diagnosis of type 1 diabetes: pragmatic randomised controlled trial and economic evaluation
Blair, J. C., McKay, A., Ridyard, C., Thornborough, K., Bedson, E., Peak, M., Didi, M., Annan, F., Gregory, J. W., Hughes, D. A. & Gamble, C., 3 Ebr 2019, Yn: British Medical Journal. 365, t. l1226 l1226.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydCore Health Outcomes in Childhood Epilepsy (CHOICE): Development of a core outcome set using systematic review methods and a Delphi survey consensus
Crudgington, H., Rogers, M., Bray, L., Carter, B., Currier, J., Gibbon, F., Hughes, D., Lyle, S., Roberts, D., Smith, C. T., Gringras, P., Pal, D. & Morris, C., Mai 2019, Yn: Epilepsia. 60, 5, t. 857-871
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydCost-effectiveness analysis of adalimumab for the treatment of uveitis associated with Juvenile Idiopathic Arthritis
Hughes, D. A., Culeddu, G., Plumpton, C. O., Wood, E., Dick, A. D., Jones, A. P., McKay, A., Williamson, P. R., Compeyrot Lacassagne, S., Hardwick, B., Hickey, H., Woo, P., Beresford, M. W. & Ramanan, A. V., Maw 2019, Yn: Ophthalmology. 126, 3, t. 415-424
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydCost-effectiveness analysis of adalimumab for the treatment of uveitis associated with Juvenile Idiopathic Arthritis: Authors’ reply.
Hughes, D., Culeddu, G., Plumpton, C., Wood, E., Dick, A. D., Beresford, M. W. & Ramanan, A. V., Maw 2019, Yn: Ophthalmology. 126, 3, t. e24-e25
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Llythyr › adolygiad gan gymheiriaid - CyhoeddwydCost-effectiveness of panel tests for multiple pharmacogenes associated with adverse drug reactions: An evaluation framework
Plumpton, C., Pirmohamed, M. & Hughes, D., Meh 2019, Yn: Clinical Pharmacology and Therapeutics. 105, 6, t. 1429-1438
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydDeveloping patient-centred, feasible alternative care for adult emergency department users with epilepsy: Protocol for the mixed-methods observational ‘Collaborate’ project.
Noble, A. J., Mathieson, A., Ridsdale, L., Holmes, E., Morgan, M., McKinlay, A., Dickson, J., Jackson, M., Hughes, D., Goodacre, S. & Marson, A. G., 2 Tach 2019, Yn: BMJ Open. 9, 11, e031696.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydEvidence to support inclusion of pharmacogenetic biomarkers in randomised controlled trials
Johnson, D., Jorgensen, A., Hughes, D. & Pirmohamed, M., 1 Medi 2019, Yn: Journal of Personalized Medicine. 9, 3, 19 t., 42.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl adolygu › adolygiad gan gymheiriaid - CyhoeddwydHealth utilities and costs for Motor Neurone Disease
Moore, A., Young, C. A. & Hughes, D., Tach 2019, Yn: Value in Health. 22, 11, t. 1257-1265
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydImproving Medication Adherence Research Reporting: European Society for Patient Adherence, Compliance and Persistence Medication Adherence Reporting Guideline
de Geest, S., Zullig, L., Dunbar-Jacobs, J., Hughes, D., Wilson, I. & Vrijens, B., Meh 2019, Yn: Journal of Cardiovascular Nursing. 34, 3, t. 199-200
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Golygyddiad › adolygiad gan gymheiriaid - CyhoeddwydImproving medication adherence research reporting: ESPACOMP Medication Adherence Reporting Guideline (EMERGE)
de Geest, S., Zullig, L. L., Dunbar-Jacob, J., Hughes, D., Wilson, I. & Vrijens, B., 1 Ebr 2019, Yn: European Journal of Cardiovascular Nursing. 18, 4, t. 258-259 2 t.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Golygyddiad › adolygiad gan gymheiriaid - CyhoeddwydIntegration of Pharmacometrics and Pharmacoeconomics to Quantify the Value of Improved Forgiveness to Nonadherence: A Case Study of Novel Xanthine Oxidase Inhibitors for Gout
Hill McManus, D., Marshall, S., Soto, E. & Hughes, D., Medi 2019, Yn: Clinical Pharmacology and Therapeutics. 106, 3, t. 652-660
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydMedicines Shortages in the United Kingdom
Hughes, D., Hyd 2019, Yn: Clinical Pharmacology and Therapeutics. 106, 4, t. 712
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Llythyr › adolygiad gan gymheiriaid - CyhoeddwydPatient-focused drug development methods for benefit-risk assessments: A case study using discrete choice experiment for antiepileptic drugs
Holmes, E. A. F., Plumpton, C., Baker, G. A., Jacoby, A., Ring, A., Williamson, P., Marson, A. & Hughes, D. A., Maw 2019, Yn: Clinical Pharmacology and Therapeutics. 105, 3, t. 672-683 12 t.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydStatistical Methods for Adjusting Estimates of Treatment Effectiveness for Patient Non-adherence in the Context of Time-to-Event Outcomes and Health Technology Assessment: A Systematic Review of Methodological Papers
Alshreef, A., Latimer, N., Tappenden, P., Wong, R., Hughes, D., Fotheringham, J. & Dixon, S., Tach 2019, Yn: Medical Decision Making. 39, 8, t. 910-925 16 t.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydSupporting people with type 2 diabetes in effective use of their medicine through mobile health technology integrated with clinical care (SuMMiT-D Feasibility): a randomised feasibility trial protocol
Farmer, A. J., Allen, J., Bartlett, K., Bower, P., Chi, Y., French, D. P., Gudgin, B., Holmes, E., Horne, R., Hughes, D., Kenning, C., Locock, L., McSharry, J., Miles, L., Newhouse, N., Rea, R., Riga, J., Tarassenko, L., Velardo, C., Williams, N., Williams, V. & Yu, L.-M., 29 Rhag 2019, Yn: BMJ Open. 9, 12, e033504.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydSystematic Review: Outcomes and adverse events from randomised trials in Crohn's disease
Catt, H., Hughes, D., Kirkham, J. K. & Bodger, K., Ebr 2019, Yn: Alimentary Pharmacology and Therapeutics. 49, 8, t. 978-996 19 t.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydValue assessment and quantitative benefit-risk modelling of biosimilar infliximab for Crohn’s disease
Catt, H., Bodger, K., Hughes, D. & Kirkham, J. J., Rhag 2019, Yn: PharmacoEconomics. 37, 12, t. 1509-1523 15 t.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydWhat really matters? A mixed methods study of treatment preferences and priorities among people with epilepsy in the UK
Ring, A., Jacoby, A., Baker, G., Holmes, E., Hughes, D., Kierans, C. & Marson, A., Meh 2019, Yn: Epilepsy and Behavior. 95, t. 181-191
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
2018
- CyhoeddwydContinuous subcutaneous insulin infusion versus multiple daily injections in children and young people at diagnosis of type 1 diabetes: the SCIPI RCT
Blair, J., McKay, A., Ridyard, C., Thornborough, K., Bedson, E., Peak, M., Didi, M., Annan, F., Gregory, J. W., Hughes, D. & Gamble, C., Awst 2018, Yn: Health Technology Assessment. 22, 42, t. 1-112 112 t.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydCore items for a standardized resource-use measure (ISRUM): expert Delphi consensus survey
Thom, J., Brookes, S. T., Ridyard, C., Riley, R., Hughes, D., Wordsworth, S., Noble, S., Thornton, G. & Hollingworth, W., Meh 2018, Yn: Value in Health. 21, 6, t. 640-649
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydCost-Effectiveness Analysis of the Use of Point-of-Care C-Reactive Protein Testing to Reduce Antibiotic Prescribing in Primary Care
Holmes, E., Harris, S. D., Hughes, A., Craine, N. & Hughes, D., 7 Rhag 2018, Yn: Antibiotics. 7, 4, 19 t., 106.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydDo guidelines for treating chest disease in children use Cochrane reviews effectively? A systematic review
Prayle, A., Cox, T., Smith, S. J., Rycroft-Malone, J., Thomas, K. S., Hughes, D. & Smyth, A. R., Gorff 2018, Yn: Thorax. 73, 7, t. 670-673
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Llythyr › adolygiad gan gymheiriaid - CyhoeddwydESPACOMP Medication Adherence Reporting Guideline (EMERGE)
De Geest, S., Zullig, L. L., Dunbar-Jacob, J., Helmy, R., Hughes, D., Wilson, I. & Vrijens, B., 3 Gorff 2018, Yn: Annals of Internal Medicine. 169, 1, t. 30-35
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydEconomics of pharmacogenetic guided treatments: Underwhelming or overstated?
Hughes, D., Mai 2018, Yn: Clinical Pharmacology and Therapeutics. 103, 5, t. 749-751
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydImpact of non-adherence and flare resolution on the cost effectiveness of treatments for gout: Application of a linked pharmacometric/pharmacoeconomic model
Hill-McManus, D., Marshall, S., Soto, E., Lane, S. & Hughes, D., Rhag 2018, Yn: Value in Health. 21, 12, t. 1373-1381
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydImpact of non-adherence on the safety and efficacy of uric acid lowering therapies in the treatment of gout
Hill McManus, D., Soto, E., Marshall, S., Lane, S. & Hughes, D., Ion 2018, Yn: British Journal of Clinical Pharmacology. 84, 1, t. 142-152
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydImpact on the phased abolition of co-payments on the utilisation of selected prescription medicines in Wales
Alam, M. F., Cohen, D., Dunstan, F., Hughes, D. & Routledge, P. A., Ion 2018, Yn: Health Economics. 27, 1, t. 236-243
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydInnovation at the Intersection of Clinical Trials and Real-World Data Science to Advance Patient Care
Swift, B., Jain, L., White, C., Chandrasekaran, V., Bhandari, A., Hughes, D. & Jadhav, P., Medi 2018, Yn: Clinical and Translational Science. 11, 5, t. 450-460 11 t.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydLessons learnt from a discontinued randomised controlled trial: Adalimumab injection compared with placebo for patients receiving physiotherapy treatment for sciatica (Subcutaneous Injection of Adalimumab Trial compared with Control: SCIATiC)
Williams, N., Jenkins, A., Goulden, N., Hoare, Z., Hughes, D., Wood, E., Foster, N. E., Walsh, D. A., Carnes, D., Sparkes, V., Hay, E. M., Isaacs, J., Konstantinou, K., Morrissey, D., Karppinen, J., Genevay, S. & Wilkinson, C., 31 Gorff 2018, Yn: Trials. 19, 408.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydLetter to the Editor. Phase III randomized controlled trials are essential to properly evaluate the role of radiotherapy in WHO grade II meningioma
Jenkinson, M., Weber, D., Haylock, B., Sherratt, F., Young, B., Weller, M., Bulbeck, H., Culeddu, G., Hughes, D., Brain, A., Das, K., Preusser, M., Francis, P. & Gamble, C., 17 Awst 2018, Yn: Journal of Neurology, Neurosurgery and Psychiatry.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Llythyr › adolygiad gan gymheiriaid - CyhoeddwydMapping ALSFRS-R and ALSUI to EQ-5D in patients with motor neurone disease
Moore, A., Young, C. A. & Hughes, D., Tach 2018, Yn: Value in Health. 21, 11, t. 1322-1329
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydNew Medicines in Wales: The All Wales Medicines Strategy Group (AWMSG) Appraisal Process and Outcomes
Varnava, A., Samuels, K., Hughes, D. & Routledge, P. A., Mai 2018, Yn: Pharmacoeconomics. 36, 5, t. 613-624 12 t.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydRare disease prevention and treatment: The need for a level playing field
Hughes, D. & Plumpton, C., Chwef 2018, Yn: Pharmacogenomics. 19, 3, t. 243-247
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydSocietal preferences for funding orphan drugs in the United Kingdom: An application of person trade off and discrete choice experiment methods
Bourke, S. M., Plumpton, C. & Hughes, D., 9 Mai 2018, Yn: Value in Health. 21, 5, t. 538-546
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
2017
- CyhoeddwydAdalimumab plus Methotrexate for Uveitis in Juvenile Idiopathic Arthritis
Ramanan, A. V., Dick, A. D., Jones, A. P., McKay, A., Williamson, P. R., Compeyrot-Lacassagne, S., Hardwick, B., Hickey, H., Hughes, D., Woo, P., Benton, D., Edelsten, C. & Beresford, M. W., 27 Ebr 2017, Yn: New England Journal of Medicine. 376, 17, t. 1637-1646
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydAffordable orphan drugs: A role for not-for-profit organisations
Davies, E. H., Fulton, E., Brook, D. & Hughes, D., Gorff 2017, Yn: British Journal of Clinical Pharmacology. 83, 7, t. 1595-1601
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydCarer-administration of as-needed sub-cutaneous medication for breakthrough symptoms in homebased dying patients: a UK study (CARIAD)
Wilkinson, C., Poolman, M., Roberts, J., Wee, B., Hiscock, J., Hughes, D., Nelson, A., Perkins, P., Johnstone, R. P., Reymond, E., Foster, B., O'Connor, J., Jones, S., Hoare, Z., Roberts, R., Byrne, A., Healy, S. & Lewis, P., 1 Medi 2017.
Allbwn ymchwil: Cyfraniad at gynhadledd › Murlen › adolygiad gan gymheiriaid - CyhoeddwydComparison of regression methods for the cost effectiveness analysis of clinical trials with a small population size: the sycamore and folated trials
Culeddu, G., Hughes, D. & Welton, N., 10 Gorff 2017.
Allbwn ymchwil: Cyfraniad at gynhadledd › Murlen › adolygiad gan gymheiriaid - CyhoeddwydContinuous Subcutaneous Infusion Versus Multiple Dose Injection of Insulin For Newly-Diagnosed T1D Paediatric Patients: A Cost-Utility Analysis
Ridyard, C., Blair, J. & Hughes, D., 20 Hyd 2017, Yn: Value in Health. 20, 9, t. A582
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydContinuous subcutaneous insulin infusion compated to multiple daily injection regimens in children and yung people at diagnosis of type 1 diabetes: A pragmatic randomised controlled trial and economic evaluation (scipi trial)
Blair, J., Mckay, A., Ridyard, C., Thornborough, K., Bedson, E., Peak, M., Didi, M., Annan, F., John, G., Hughes, D. & Gamble, C., Medi 2017, t. 22-23.
Allbwn ymchwil: Cyfraniad at gynhadledd › Crynodeb › adolygiad gan gymheiriaid - CyhoeddwydCore items for a standardised resource-use measure (ISRUM):expert Delphi consensus survey
Thorn, J., Ridyard, C., Riley, R., Brookes, S., Hughes, D., Wordsworth, S., Noble, S., Thornton, G. & Hollingworth, W., 7 Mai 2017, t. P265. 1 t.
Allbwn ymchwil: Cyfraniad at gynhadledd › Murlen › adolygiad gan gymheiriaid - CyhoeddwydCost effectiveness analysis of HLA-B*58:01 genotyping prior to initiation of allopurinol for gout
Plumpton, C., Alfirevic, A., Pirmohamed, M. & Hughes, D., 1 Hyd 2017, Yn: Rheumatology. 56, 10, t. 1729-1739
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydCost-effectiveness of HLA-B*15:02 screening in Malaysia
Plumpton, C. & Hughes, D., Hyd 2017, Yn: British Journal of Dermatology. 177, 4, t. 904-905
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Sylw/Dadl - CyhoeddwydCost-effectiveness of paediatric central venous catheters in the UK: A secondary publication from the CATCH clinical trial
Ridyard, C., Plumpton, C., Gilbert, R. E. & Hughes, D., 19 Medi 2017, Yn: Frontiers in Pharmacology. 8, 644.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydDecision analytic modelling methods for the assessing the effectiveness of treatment sequences for clinical and economic decision making: a methodological review
Lewis, R., Hughes, D. & Wilkinson, C., 30 Tach 2017, Yn: Value in Health. 20, 9, t. A748 1 t.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydEconomic Studies in Motor Neurone Disease: A Systematic Methodological Review
Moore, A., Young, C. A. & Hughes, D., Ebr 2017, Yn: Pharmacoeconomics. 35, 4, t. 397-413
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydHealth economics analysis plans: the current state of play
Thorn, J., Ridyard, C., Hughes, D., Wordsworth, S., Mihaylova, B., Noble, S. & Hollingworth, W., 7 Mai 2017, t. P144. 1 t.
Allbwn ymchwil: Cyfraniad at gynhadledd › Murlen › adolygiad gan gymheiriaid - CyhoeddwydPatient preferences for outcomes in clinical trials: implications for medicines optimization
Holmes, E., Marson, A. G. & Hughes, D., 8 Mai 2017, Yn: Trials. 18 (Suppl 1), O18, t. 192 1 t.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Crynodeb Cyfarfod › adolygiad gan gymheiriaid - CyhoeddwydPatient-level information and costing systems (PLICS) as a source of routinely collected cost data for trial-based economic evaluations
Ridyard, C. & Hughes, D., 7 Mai 2017, t. P141. 1 t.
Allbwn ymchwil: Cyfraniad at gynhadledd › Murlen › adolygiad gan gymheiriaid - CyhoeddwydPatterns In Working Days Lost By Parents Of Children Newly-Diagnosed With Type 1 Diabetes (T1D)
Ridyard, C., Blair, J. & Hughes, D., 20 Hyd 2017, Yn: Value in Health. 20, 9, t. A590
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydPump-Downloaded Insulin Usage For The First 12 Months In A Cohort of Children Newly-Diagnosed With Type 1 Diabetes (T1D)
Ridyard, C., Blair, J. & Hughes, D., Tach 2017, Yn: Value in Health. 20, 9, t. A481 - A482
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydRenal transplant patients’ preference for the supply and delivery of immunosuppressants in Wales: A discrete choice experiment
Hagemi, A., Plumpton, C. & Hughes, D., 2 Hyd 2017, Yn: BMC Nephrology. 18, 305.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydSocietal perspective on access to publicly subsidised medicines: A cross sectional survey of 3080 adults in Australia
Chim, L., Salkeld, G., Kelly, P., Lipworth, W., Hughes, D. & Stockler, M., 1 Maw 2017, Yn: PLoS ONE.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydSubcutaneous Injection of Adalimumab Trial compared with Control (SCIATiC): a randomised controlled trial of adalimumab injection compared with placebo for patients receiving physiotherapy treatment for sciatica
Williams, N. H., Jenkins, A., Goulden, N., Hoare, Z., Hughes, D. A., Wood, E., Foster, N. E., Walsh, D. A., Carnes, D., Sparkes, V., Hay, E. M., Isaacs, J., Konstantinou, K., Morrissey, D., Karppinen, J., Genevay, S. & Wilkinson, C., 31 Hyd 2017, Yn: Health Technology Assessment. 21, 60, t. 1-180 180 t.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydUse Of The Ims Core Diabetes Model (CDM) In A Long-Term Projected Health Economic Comparison Of CSII And MDI Treatments Of Type 1 Diabetes (T1D) In A Newly-Diagnosed Population Of Paediatric Patients
Ridyard, C., Blair, J. & Hughes, D., 20 Hyd 2017, Yn: Value in Health. 20, 9, t. A580
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydUsing Routinely Recorded Data in the UK to Assess Outcomes in a Randomised Controlled Trial: The Trials of Access
Powell, G., Bonnett, L., Smith, C. T., Hughes, D., Williamson, P. & Marson, A., 23 Awst 2017, Yn: Trials. 18, 11 t., 389.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
2016
- Cyhoeddwyd2016 Prof. John Urquhart Obituary
Breckenridge, A. & Hughes, D., Awst 2016, Yn: British Journal of Clinical Pharmacology. 82, 2, t. 573
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Llythyr › adolygiad gan gymheiriaid - CyhoeddwydA randomised, patient-assessor blinded, sham-controlled trial of external noninvasive peripheral nerve stimulation for chronic neuropathic pain following peripheral nerve injury (EN-PENS trial): study protocol for a randomised controlled trial
Johnson, S., Goebel, A., Richey, R., Holmes, E. & Hughes, D., 6 Rhag 2016, Yn: Trials. 17, 574.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydA systematic review of economic evaluations of pharmacogenetic testing for prevention of adverse drug reactions
Plumpton, C. O., Roberts, D., Pirmohamed, M. & Hughes, D. A., Awst 2016, Yn: Pharmacoeconomics. 34, 8, t. 771-793
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydA systematic review of patients' perspectives on the subcutaneous route of medication administration
Ridyard, C., Dawoud, D. M., Tuersley, L. V. & Hughes, D., Awst 2016, Yn: Patient: Patient–Centered Outcomes Research. 9, 4, t. 281-292
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydCATheter Infections in CHildren (CATCH): a randomised controlled trial and economic evaluation comparing impregnated and standard central venous catheters in children
Harron, K., Mok, Q., Dwan, K., Ridyard, C., Mott, T., Millar, M., Ramnarayan, P., Tibby, S. M., Muller-Pebody, B., Hughes, D., Gamble, C. & Gilbert, R. E., Maw 2016, Yn: Health Technology Assessment. 20, 18
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydConducting Economic Evaluations Alongside Randomised Trials: Current Methodological Issues and Novel Approaches
Hughes, D., Charles, J. M., Dawoud, D. M., Edwards, R. T., Holmes, E. A., Jones, C. L., Parham, P., Plumpton, C., Ridyard, C. O., Lloyd-Williams, H., Wood, E. M. & Yeo, S., Mai 2016, Yn: Pharmacoeconomics. 34, 5, t. 447-461
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydCost-effectiveness of pharmacogenetic-guided dosing of warfarin in the United Kingdom and Sweden
Verhoef, T. I., Redekop, W. K., Langenskiold, S., Kamali, F., Wadelius, M., Burnside, G., Maitland-van der Zee, A. H., Hughes, D. & Pirmohamed, M., Hyd 2016, Yn: The Pharmacogenomics Journal. 16, t. 478–484
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydGeneralisability and Cost-Impact of Antibiotic-Impregnated Central Venous Catheters for Reducing Risk of Bloodstream Infection in Paediatric Intensive Care Units in England
Harron, K., Mok, Q., Hughes, D., Muller-Pebody, B., Parslow, R., Ramnarayan, P. & Gilbert, R., 21 Maw 2016, Yn: PLoS ONE. 11, 3, t. e0151348
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydHealth Economics Analysis Plans: Where Are We Now?
Thorn, J., Ridyard, C., Hughes, D., Wordsworth, S., Mihaylova, B., Noble, S. & Hollingworth, W., 3 Tach 2016, t. A397. 1 t.
Allbwn ymchwil: Cyfraniad at gynhadledd › Murlen › adolygiad gan gymheiriaid - CyhoeddwydImpregnated central venous catheters for prevention of bloodstream infection in children (the CATCH trial): a randomised controlled trial
Gilbert, R. E., Mok, Q., Dwan, K., Harron, K., Moitt, T., Millar, M., Ramnarayan, P., Tibby, S. M., Hughes, D. & Gamble, C. F., 23 Ebr 2016, Yn: The Lancet. 387, 10029, t. 1732-1742
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydMultiple imputation of multiple multi-item scales when a full imputation model is infeasible
Hughes, D., Plumpton, C. O., Morris, T., Hughes, D. A. & White, I. R., 26 Ion 2016, Yn: BMC Research Notes. 9, 45, t. 1-15
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydOpportunity costs and local health service spending decisions: a qualitative study from Wales
Schaffer, S. K., Sussex, J., Hughes, D. & Devlin, N., 25 Maw 2016, Yn: BMC Health Services Research. 16, 103
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydProfitability and Market Value of Orphan Drug Companies: A Retrospective, Propensity-Matched Case-Control Study
Hughes, D. & Poletti-Hughes, J., 21 Hyd 2016, Yn: PLoS ONE. 11, 10, e0164681.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydWhat influences persistence with medicines? A multinational discrete choice experiment of 2549 patients
Holmes, E. A., Morrison, V. L. & Hughes, D., Awst 2016, Yn: British Journal of Clinical Pharmacology. 82, 2, t. 522-531
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
2015
- CyhoeddwydAdherence of patients to long-term medication: a cross-sectional study of antihypertensive regimens in Austria
Lotsch, F., Auer-Hackenberg, L., Groger, M., Rehman, K., Morrison, V. L., Holmes, E. A., Parveen, S., Plumpton, C. O., Clyne, W., de Geest, S., Dobbels, F., Vrijens, B., Kardas, P., Hughes, D. & Ramharter, M., Mai 2015, Yn: Wiener klinische Wochenschrift. 127, 9-10, t. 379-384
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydClimate influences on the cost-effectiveness of vector-based interventions against malaria in elimination scenarios
Hughes, D., Parham, P. E. & Hughes, D. A., 16 Chwef 2015, Yn: Philosophical Transactions B: Biological Sciences. 370, 1665
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydCost-effectiveness of screening for HLA-A*31:01 prior to initiation of carbamazepine in epilepsy
Plumpton, C., Yip, V. L. M., Alfirevic, A., Marson, A. G., Pirmohamed, M. & Hughes, D., Ebr 2015, Yn: Epilepsia.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydEconomic evaluation of a behavior-modifying intervention to enhance antiepileptic drug adherence
Hughes, D., Plumpton, C. O., Brown, I., Reuber, M., Marson, A. G. & Hughes, D. A., 26 Maw 2015, Yn: Epilepsy and Behavior. 45, t. 180-186
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydEvaluation of a consultant audit and feedback programme to improve the quality of antimicrobial prescribing in acute medical admissions
Hughes, D., Roberts, E., Dawoud, D. M., Hughes, D. A. & Cefai, C., 1 Hyd 2015, Yn: International Journal of Pharmacy Practice. 23, 5, t. 333-339
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydIdentification Of Items For A Standardised Resource-Use Measure: Review Of Current Instruments
Thorn, J. C., Ridyard, C., Riley, R., Brookes, S., Hughes, D., Wordsworth, S., Noble, S. & Hollingworth, W., Tach 2015.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur › adolygiad gan gymheiriaid - CyhoeddwydNICE recommendations: why no disinvestment recommendations to offset investment decisions?
Hughes, D., Tuersley, L. V., Hughes, D. A., Wood, E. M. & Tuersley, L., 19 Mai 2015, Yn: BMJ. 350
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydPharmacogenetic testing prior to carbamazepine treatment of epilepsy: 1 patients’ and physicians’ preferences for testing and service delivery
Powell, G., Holmes, E. A., Plumpton, C. O., Ring, A., Baker, G. A., Jacoby, A., Pirmohamed, M., Marson, A. G. & Hughes, D. A., 3 Gorff 2015, Yn: British Journal of Clinical Pharmacology. 80, 5, t. 1149-1159
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydPredictors of Self-Reported Adherence to Antihypertensive Medicines: A Multinational, Cross-Sectional Survey
Morrison, V. L., Holmes, E. A., Parveen, S., Plumpton, C. O., Clyne, W., De Geest, S., Dobbels, F., Vrijens, B., Kardas, P. & Hughes, D., Maw 2015, Yn: Value in Health. 18, 2, t. 206-216
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydRare Disease Terminology and Definitions—A Systematic Global Review: Report of the ISPOR Rare Disease Special Interest Group
Hughes, D., Richter, T., Nestler-Parr, S., Babela, R., Khan, Z. M., Tesoro, T., Molsen, E. & Hughes, D. A., 18 Awst 2015, Yn: Value in Health. 18, 6, t. 906-914
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydReview of resource-use measures in UK economic evaluations
Ridyard, C. & Hughes, D., 2015, PSSRU Unit Costs of Health and Social Care 2015 . Curtis, L. & Burns, A. (gol.). University of Kent, Canterbury, t. 22-31 10 t.
Allbwn ymchwil: Pennod mewn Llyfr/Adroddiad/Trafodion Cynhadledd › Pennod › adolygiad gan gymheiriaid - CyhoeddwydStudy protocol for a randomised controlled trial of insulin delivery by continuous subcutaneous infusion compared to multiple daily injections
Blair, J., Gregory, J., Hughes, D., Ridyard, C., Gamble, C., McKay, A., Didi, M., Thornborough, K., Bedson, E., Awoyale, L., Cwiklinski, E. & Peak, M., 16 Ebr 2015, Yn: Trials. 16, 163.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydTaxonomy for methods of resource use measurement
DIRUM Team, 23 Ion 2015, Yn: Health Economics. 24, 3, t. 372-378
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Llythyr › adolygiad gan gymheiriaid - CyhoeddwydThe ROAM/EORTC-1308 trial: Radiation versus Observation following surgical resection of Atypical Meningioma: study protocol for a randomised controlled trial
Jenkinson, M. D., Javadpour, M., Haylock, B. J., Young, B., Gillard, H., Vinten, J., Bulbeck, H., Das, K., Farrell, M., Looby, S., Hickey, H., Preusser, M., Mallucci, C. L., Hughes, D., Gamble, C. & Weber, D. C., 14 Tach 2015, Yn: Trials. 16
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - Cyhoeddwyd‘Seizure First Aid Training’ for people with epilepsy who attend emergency departments, and their family and friends: study protocol for intervention development and a pilot randomised controlled trial
Noble, A. J., Marson, A. G., Tudur-Smith, C., Morgan, M., Hughes, D., Goodacre, S. & Ridsdale, L., 24 Gorff 2015, Yn: BMJ Open. 5, 7
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
2014
- CyhoeddwydA randomised controlled trial of the clinical effectiveness, safety and cost-effectiveness of adalimumab in combination with methotrexate for the treatment of juvenile idiopathic arthritis associated uveitis (SYCAMORE Trial)
Hughes, D., Ramanan, A., Dick, A. D., Benton, D., Compeyrot-Lacassagne, S., Dawoud, D., Hardwick, B., Hickey, H., Hughes, D. A., Jones, A., Woo, P., Edelsten, C., Beresford, M. W. & The SYCAMORE Trail Management Group, [. V., 9 Ion 2014, Yn: Trials. 15, 14
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydDoes Electronic Monitoring Influence Adherence to Medication? Randomized Controlled Trial of Measurement Reactivity
Hughes, D., Sutton, S., Kinmonth, A. L., Hardeman, W., Hughes, D. A., Boase, S., Prevost, T., Kellar, I., Graffy, J., Griffin, S. & Farmer, A., 1 Rhag 2014, Yn: Annals of Behavioral Medicine. 48, 3, t. 293-299
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydFolate Augmentation of Treatment-Evaluation for Depression (FolATED): randomised trial and economic evaluation
Bedson, E., Bell, D., Carr, D., Carter, B., Hughes, D., Jorgensen, A., Lewis, H., Lloyd, K., McCaddon, A., Moat, S., Pink, J., Pirmohamed, M., Roberts, S., Russell, I., Sylvestre, Y., Tranter, R., Whitaker, R., Wilkinson, C. & Williams, N., Gorff 2014, Yn: Health Technology Assessment. 18, 48, t. 1-159
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydPredicting Adherence to Medications Using Health Psychology Theories: A Systematic Review of 20 Years of Empirical Research
Holmes, E. A., Morrison, V. L. & Hughes, D., 8 Rhag 2014, Yn: Value in Health. 17, 8, t. 863-876
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydThe British antibiotic and silver-impregnated catheters for ventriculoperitoneal shunts multi-centre randomised controlled trial (the BASICS trial): study protocol
Hughes, D., Jenkinson, M. D., Gamble, C., Hartley, J. C., Hickey, H., Hughes, D. A., Blundell, M., Griffiths, M. J., Solomon, T. & Malluci, C. L., 3 Ion 2014, Yn: Trials. 15, 14
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydValuations of epilepsy-specific health states: a comparison of patients with epilepsy and the general population
Hughes, D., Mulhern, B., Rowen, D., Snape, D., Jacoby, A., Marson, T., Hughes, D. A., Baker, G. & Brazier, J., 1 Gorff 2014, Yn: Epilepsy and Behavior. 36, t. 12-17
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
2013
- CyhoeddwydA Systematic Review of Patient Preferences for Subcutaneous Medications
Ridyard, C., Dawoud, D. & Hughes, D., Tach 2013.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur › adolygiad gan gymheiriaid - CyhoeddwydAdherence and variability in warfarin dose requirements: assessment in a prospective cohort
Hughes, D., Jorgensen, A. L., Hughes, D. A., Hanson, A., van Eker, D., Toh, C. H., Pirmohamed, M. & Williamson, P. R., 1 Ion 2013, Yn: Pharmacogenomics. 14, 2, t. 151-163
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydComparative Effectiveness of Dabigatran, Rivaroxaban, Apixaban, and Warfarin in the Management of Patients With Nonvalvular Atrial Fibrillation
Hughes, D., Pink, J., Pirmohamed, M. & Hughes, D. A., 25 Ebr 2013, Yn: Clinical Pharmacology and Therapeutics.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydCost effectiveness of pharmacogenetic screening prior to initiation of carbamazepine treatment for epilepsy
Plumpton, C. O., Yip, V., Alfirevic, A., Marson, A., Pirmohamed, M. & Hughes, D., Tach 2013, Yn: Value in Health. 16, 7, t. A624-A624
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydCost-Effectiveness of Pharmacogenetics-Guided Warfarin Therapy vs. Alternative Anticoagulation in Atrial Fibrillation
Hughes, D., Pink, J., Pirmohamed, M., Lane, S. & Hughes, D. A., 23 Medi 2013, Yn: Clinical Pharmacology and Therapeutics.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydDecision-Makers’ Preferences for Approving New Medicines in Wales: A Discrete-Choice Experiment with Assessment of External Validity
Hughes, D., Linley, W. G. & Hughes, D. A., 1 Ebr 2013, Yn: Pharmacoeconomics. 31, 4, t. 345-355
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydIdentification and Assessment of Adherence-Enhancing Interventions in Studies Assessing Medication Adherence Through Electronically Compiled Drug Dosing Histories: A Systematic Literature Review and Meta-Analysis
Hughes, D., Holmes, E. A., Demonceau, J., Ruppar, T., Kristano, P., Hughes, A. D., Fargher, E., Przemyslaw, K., De Geest, S., Dobbels, F., Lewek, P., Urquhart, J. & Vrijens, B., 1 Mai 2013, Yn: Drugs. 73, 6, t. 545-562
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydImpact of Interventions on Medication Adherence and Blood Pressure Control in Patients with Essential Hypertension: A Systematic Review by the ISPOR Medication Adherence and Persistence Special Interest Group
Hughes, D., Gwadry-Sridhar, F. H., Manias, E., Lal, L., Salas, M., Hughes, D. A., Ratzki-Leewing, A. & Grubisic, M., 1 Gorff 2013, Yn: Value in Health. 16, 5, t. 863-871
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydInterventions to improve osteoporosis medication adherence and persistence: a systematic review and literature appraisal by the ISPOR Medication Adherence & Persistence Special Interest Group
Hughes, D., Linck, P. G., Hiligsmann, M., Salas, M., Hughes, D. A., Manias, E., Gwadry-Sridhar, F. H., Linck, P. & Cowell, W., 1 Rhag 2013, Yn: Osteoporosis International. 24, 12, t. 2907-2918
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydNew advice on switching antiepileptic drugs might be a false economy
Holmes, E. A., Plumpton, C. O., Hughes, D., Holmes, E., Plumpton, C., Duerden, M., Marson, T. & Hughes, D. A., 16 Rhag 2013, Yn: British Medical Journal. 347
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydPharmacogenetic tests: the need for a level playing field
Hughes, D., Pirmohamed, M. & Hughes, D. A., 1 Ion 2013, Yn: Nature Reviews Drug Discovery. 12, 3-4
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydResource-Use Measurement Based on Patient Recall: Issues and Challenges for Economic Evaluation
Thorn, J. C., Coast, J., Cohen, D., Hollingworth, W., Knapp, M., Noble, S. M., Ridyard, C. H., Wordsworth, S. & Hughes, D., 1 Meh 2013, Yn: Applied Health Economics and Health Policy. 11, 3, t. 155-161
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydReview of the Use of Resource Use Instruments Based on Patient Recall in Relation to Other Methods of Cost Estimation
Ridyard, C. & Hughes, D., Tach 2013.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur › adolygiad gan gymheiriaid - CyhoeddwydReview of the use of resource use instruments based on patient recall in relation to other methods of resource use estimation
Ridyard, C. & Hughes, D., Tach 2013.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur › adolygiad gan gymheiriaid - CyhoeddwydScreening log data can be used to inform protocol modifications, increasing patient recrutiment to a challanging clinical trial
Blair, J., Awoyale, L., Thornborough, K., Peak, M., Didi, M., Bedson, E., Hughes, D., Ridyard, C., Tat, T. & Gregory, J., Tach 2013.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur › adolygiad gan gymheiriaid - CyhoeddwydSocietal views on NICE, cancer drugs fund and value-based pricing criteria for prioritising medicines: a cross-sectional survey of 4118 adults in Great Britain
Hughes, D., Linley, W. G. & Hughes, D. A., 1 Awst 2013, Yn: Health Economics. 22, 8, t. 948-964
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
2012
- CyhoeddwydA Risk–Benefit Assessment of Prasugrel, Clopidogrel, and Genotype-Guided Therapy in Patients Undergoing Percutaneous Coronary Intervention
Hughes, D., Guzauskas, G. F., Hughes, D. A., Bradley, S. M. & Veenstra, D. L., 28 Maw 2012, Yn: Clinical Pharmacology and Therapeutics.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydA new taxonomy for describing and defining adherence to medications
Holmes, E. A., Hughes, D., Morrison, V. L., Vrijens, B., De Geest, S., Hughes, D. A., Prezemyslaw, K., Demonceau, J., Ruppar, T., Dobbels, F., Fargher, E., Morrison, V., Lewek, P., Matyjaszczyk, M., Mshelia, C., Clyne, W., Aronson, J. K. & Urquhart, J., 1 Mai 2012, Yn: British Journal of Clinical Pharmacology. 73, 5, t. 691-705
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydAn agenda for UK clinical pharmacology Pharmacoeconomics
Hughes, D. & Hughes, D. A., 1 Meh 2012, Yn: British Journal of Clinical Pharmacology. 73, 6, t. 968-972
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydAn explanatory randomised controlled trial of a nurse-led, consultation-based intervention to support patients with adherence to taking glucose lowering medication for type 2 diabetes
Hughes, D., Farmer, A., Hardeman, W., Hughes, D. A., Prevost, A. T., Kim, Y., Craven, A., Oke, J., Boase, S., Selwood, M., Kellar, I., Graffy, J., Griffin, S., Sutton, S. & Kinmonth, A. L., 5 Ebr 2012, Yn: BMC Family Practice. 13, 30
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydChallenges in the Development and Reimbursement of Personalized Medicine—Payer and Manufacturer Perspectives and Implications for Health Economics and Outcomes Research: A Report of the ISPOR Personalized Medicine Special Interest Group
Hughes, D., Faulkner, E., Annemans, L., Garrison, L., Helfand, M., Holtorf, A. P., Hornberger, J., Hughes, D. A., Li, T., Malone, D., Payne, K., Siebert, U., Towse, A., Veenstra, D. & Watkins, J., 1 Rhag 2012, Yn: Value in Health. 15, 8, t. 1162-1171
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydCost–effectiveness of pharmacogenetics in anticoagulation: international differences in healthcare systems and costs
Hughes, D., Verhof, T. I., Redekop, W. K., van Schie, R. M., Bayat, S., Daly, A. K., Geitona, M., Haschke-Becher, E., Hughes, D. A., Kamali, F., Levin, L. A., Manolopoulos, V. G., Pirmohamed, M., Siebert, U., Stingl, J. C., Wadelius, M., de Boer, A. & Maitland-van der Zee, A. H., 1 Medi 2012, Yn: Pharmacogenomics. 13, 12, t. 1405-1417
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydDefining rewardable innovation in drug therapy
Hughes, D., Aronson, J. K., Ferner, R. E. & Hughes, D. A., 1 Ebr 2012, Yn: Nature Reviews Drug Discovery. 11, t. 253-254
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydDevelopment of a Database of Instruments for Resource-Use Measurement: Purpose, Feasibility, and Design
DIRUM Team, 1 Gorff 2012, Yn: Value in Health. 15, 5, t. 650-655
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydMechanism-Based Approach to the Economic Evaluation of Pharmaceuticals: Pharmacokinetic/Pharmacodynamic/Pharmacoeconomic Analysis of Rituximab for Follicular Lymphoma.
Hughes, D., Pink, J., Lane, S. & Hughes, D. A., 19 Maw 2012, Yn: Pharmacoeconomics.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydReimbursement Decisions of the All Wales Medicines Strategy Group
Hughes, D., Linley, W. G. & Hughes, D. A., 1 Medi 2012, Yn: PharmoEconomics. 30, 9, t. 779-794
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydThe Population Pharmacokinetics of R and S-Warfarin: Effect of Genetic and Clinical Factors
Hughes, D., Lane, S., Al-Zubiedi, S., Hatch, E., Matthews, I., Jorgensen, A. L., Deloukas, P., Daly, A. K., Aarons, L., Ogungbenro, K., Kamali, F., Hughes, D. A. & Pirmohamed, M., 1 Ion 2012, Yn: British Journal of Clinical Pharmacology. 73, 1, t. 66-76
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydThe development of a QALY measure for epilepsy: NEWQOL-6D
Hughes, D., Mulhern, B., Rowen, D., Jacoby, A., Marson, T., Snape, D., Hughes, D. A., Latimer, N., Baker, G. A. & Brazier, J. E., 1 Mai 2012, Yn: Epilepsy and Behavior. 24, 1, t. 36-43
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
2011
- CyhoeddwydDabigatran etexilate versus warfarin in management of non-valvular atrial fibrillation in UK context: quantitative benefit-harm and economic analyses
Hughes, D., Pink, J., Lane, S., Pirmohamed, M. & Hughes D.A., [. V., 31 Hyd 2011, Yn: British Medical Journal. 343, t. 1-14
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydHTAs and rare diseases: How to assess their cost-effectiveness
Hughes, D., Phillips, C. J. & Hughes, D. A., 1 Tach 2011, Yn: Pharmaceuticals Policy and Law. 13, 3-4, t. 161-165
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydInvolving colleagues can be challenging
Fargher , E. & Hughes, D., 2 Ebr 2011, Yn: Pharmaceutical Journal. 286, t. 404
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Llythyr › adolygiad gan gymheiriaid - CyhoeddwydValue-Based Pricing: Incentive for Innovation or Zero Net Benefit?
Hughes, D. & Hughes, D. A., 1 Medi 2011, Yn: Pharmacoeconomics. 29, 9, t. 731-735
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
2010
- CyhoeddwydA systematic review of cost–effectiveness analyses of pharmacogenetic-guided dosing in treatment with coumarin derivatives
Hughes, D., Verhoef, T. I., Redekop, W. K., Darba, J., Geitona, M., Hughes, D. A., Siebert, U., de Boer, A., Maitland-van der Zee, A. H., Barallon, R., Briz, M., Daly, A., Haschke-Becher, E., Kamali, F., Kirchheiner, J., Manolopoulos, V. G., Pirmohamed, M., Rosendaal, F. R., van Schie, R. M. & Wadelius, M., 1 Gorff 2010, Yn: Pharmacogenomics. 11, 7, t. 989-1002
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydAbolition of prescription charges in Wales: the impact on medicines use in those who used to pay
Hughes, D., Groves, S., Cohen, D., Alam, M. F., Dunstan, F. D., Routledge, P. A., Hughes, D. A. & Myles, S., 1 Rhag 2010, Yn: International Journal of Pharmacy Practice. 18, 6, t. 332-340
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydAbolition of prescription copayments in Wales: an observational study on dispensing rates.
Hughes, D., Cohen, D., Alam, M. F., Dunstan, F. D., Myles, S., Hughes, D. A. & Routledge, P. A., 1 Awst 2010, Yn: Value in Health. 13, 5, t. 675-680
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydBiosimilars: Evidential standards for health technology assessment.
Hughes, D. & Hughes, D. A., 1 Maw 2010, Yn: Clinical Pharmacology and Therapeutics. 87, 3, t. 257-261
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydEnhancing methodical approaches for studying bilingualism in healthcare communication: report of a trial feasibility study.
Roberts, G. W., Hughes, D., Roberts, G., Owen, H., Hughes, L., Whitaker, R., Deuchar, M., Hughes, D. A., Llewelyn, S., John, S., Irvine, F., Owen, B. & Rowlands, A., 1 Ion 2010.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydFrom NCE to NICE: the role of pharmacoeconomics
Hughes, D. & Hughes, D. A., 1 Medi 2010, Yn: British Journal of Clinical Pharmacology. 70, 3, t. 317-319
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydGeneric and therapeutic substitutions in the UK: are they a good thing?
Hughes, D., Duerden, M. G. & Hughes, D. A., 1 Medi 2010, Yn: British Journal of Clinical Pharmacology. 70, 3, t. 335-341
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydIs exercise effective in promoting mental well-being in older age? A systematic review.
Hughes, D., Linck, P. G., Windle, G., Hughes, D. A., Linck, P., Russell, I. T. & Woods, R. T., 1 Awst 2010, Yn: Aging and Mental Health. 14, 6, t. 652-669
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydMethods for the collection of resource use data within clinical trials: A systematic review of studies funded by the UK Health Technology Assessment Program
Ridyard, C. H. & Hughes, D., 1 Rhag 2010, Yn: Value in Health. 13, 8, t. 867-872
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydNICE and new: appraising innovation.
Hughes, D., Ferner, R. E., Hughes, D. A. & Aronson, J. K., 5 Ion 2010, Yn: British Medical Journal. 340, t. b5493
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydNew drugs for old: disinvestment and NICE.
Hughes, D., Hughes, D. A. & Ferner, R. E., 25 Chwef 2010, Yn: British Medical Journal. 340, t. c572
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydThe problem of orphan drugs
Hughes, D., Ferner, R. E. & Hughes, D. A., 16 Tach 2010, Yn: British Medical Journal. 341, t. 335-341
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
2009
- CyhoeddwydA Framework for Planning and Critiquing Medication Compliance and Persistence Research Using Prospective Study Designs.
Hughes, D., Gwadry-Sridhar, F. H., Manias, E., Zhang, Y., Roy, A., Yu-Isenberg, K., Hughes, D. A. & Nichol, M. B., 1 Chwef 2009, Yn: Clinical Therapeutics. 31, 2, t. 421-435
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydA systematic review and empirical analysis of the relation between dose and duration of drug action.
Hughes, D., Hughes, D. A. & Aronson, J. K., 1 Ion 2009, t. TP40.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydAll Wales Medicines Strategy Group Final Appraisal Report - Ambrisentan (Volibris) for pulmonary arterial
hypertension.
Hughes, D., Hughes, D. A. & All Wales Strategy Group., [. V., 1 Ion 2009, 2009 gol. Unknown.
Allbwn ymchwil: Llyfr/Adroddiad › Adroddiad Comisiwn - CyhoeddwydAll Wales Medicines Strategy Group Final Appraisal Report - Anidulafungin (Ecalta) for the treatment of invasive candidiasis in adult non-neutropenic patients.
Hughes, D., Hughes, D. A. & All Wales Strategy Group., [. V., 1 Ion 2009, 2009 gol. Unknown.
Allbwn ymchwil: Llyfr/Adroddiad › Adroddiad Comisiwn - CyhoeddwydAll Wales Medicines Strategy Group Final Appraisal Report - Maraviroc (Celsentri) for treatment-experienced adults infected only with CCR5-tropic HIV-1.
Hughes, D., Hughes, D. A. & All Wales Strategy Group., [. V., 1 Ion 2009, 2009 gol. Unknown.
Allbwn ymchwil: Llyfr/Adroddiad › Adroddiad Comisiwn - CyhoeddwydAll Wales Medicines Strategy Group Final Appraisal Report - Tacrolimus (Advagraf) for the prophylaxis of transplant rejection in adult kidney or liver allograft recipients and the treatment of allograft rejection resistant to treatment with other immunosuppressive medicinal products in adult patients.
Hughes, D., Hughes, D. A. & All Wales Strategy Group., [. V., 1 Ion 2009, 2009 gol. Unknown.
Allbwn ymchwil: Llyfr/Adroddiad › Adroddiad Comisiwn - CyhoeddwydAssessment, Determinants & Economics of Medication Compliance & Persistence Forum.
Hughes, D., Hughes, D. A., Gwadry-Sridhar, F. & Manias, E., 1 Ion 2009.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydBiosimilars: Evidential standards for health technology assessment.
Hughes, D. & Hughes, D. A., 1 Ion 2009.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydBiosimilars: Evidential standards for health technology assessment.
Hughes, D. & Hughes, D. A., 1 Ion 2009.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydComparisons between the medication possession ratio (MPR) and gaps measures of medication compliance: are we selling ourselves short by relying on the MPR?
Hughes, D., Nichol, M., Manias, E., Hughes, D. A. & Schabert, V. F., 1 Ion 2009.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydCost and clinical consequence of antibiotic non-adherence in acute exacerbations of chronic bronchitis.
Sorensen, S. V., Baker, T., Fleurence, R., Dixon, J., Roberts, C., Haider, S. & Hughes, D., 1 Awst 2009, Yn: International Journal of Tuberculosis and Lung Disease. 13, 8, t. 945-954
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydCost-effectiveness of biological therapy for Crohn's disease: Markov cohort analyses incorporating United Kingdom patient-level cost data.
Hughes, D., Bodger, K., Kikuchi, T. & Hughes, D. A., 1 Awst 2009, Yn: Alimentary Pharmacology and Therapeutics. 30, 3, t. 265-274
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydCosts of Medication Nonadherence in Patients with Diabetes Mellitus: A Systematic Review and Critical Analysis of the Literature.
Hughes, D., Salas, M., Hughes, D. A., Zuluaga, A., Vardeva, K. & Lebmeier, M., 1 Medi 2009, Yn: Value in Health. 12, 6, t. 915-922
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydDrug evaluation and pharmocoeconomics.
Hughes, D., Krska, J., Hughes, D. A., Winfield, A. J. (Golygydd), Rees, J. A. (Golygydd) & Smith, I. (Golygydd), 1 Ion 2009, Pharmaceutical Practice: 4th Edition.. 2009 gol. Churchill Livingstone, t. 185-198
Allbwn ymchwil: Pennod mewn Llyfr/Adroddiad/Trafodion Cynhadledd › Pennod - CyhoeddwydEconomic evaluation of infliximab and adalimumab for Crohn's disease.
Hughes, D., Hughes, D. A., Bodger, K. & Kikuchi, T., 1 Ion 2009.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydEngaging with the MRC Methodology Hubs – NWHTMR.
Hughes, D. & Hughes, D. A., 1 Ion 2009.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydEstimating Drug Costs in Economic Evaluations in Ireland and the UK: An Analysis of Practice and Research Recommendations.
Hughes, D., Hughes, D. A., Tilson, L. & Drummond, M. F., 1 Mai 2009, Yn: Pharmacoeconomics. 27, 8, t. 635-643
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydFollow-up of cancer in primary care versus secondary care: systematic review
Lewis, R. A., Neal, R. D., Williams, N. H., France, B., Hendry, M., Russell, D., Hughes, D. A., Russell, I., Stuart, N. S. A., Weller, D. & Wilkinson, C., 1 Gorff 2009, Yn: British Journal of General Practice. 59, 564, t. e234-e247
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydGenetic and environmental factors determining clinical outcomes and cost of warfarin therapy: a prospective study.
Hughes, D., Jorgensen, A. L., Al-Zubiedi, S., Zhang, J. E., Keniry, A., Hanson, A., Hughes, D. A., Van Eker, D., Stevens, L., Hawkins, K., Toh, C. H., Kamali, F., Daly, A. K., Fitzmaurice, D., Coffey, A., Williamson, P. R., Park, B. K., Deloukas, P. & Pirmohamed, M., 1 Hyd 2009, Yn: Pharmacogenetics and Genomics. 19, 10, t. 800-812
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydImpact of pharmacogenetics on the costs of managing adverse events with warfarin: A prospective analysis.
Hughes, D., Hughes, D. A., Al-Zubiedi, S., Hanson, A., Jorgensen, A. & Pirmohamed, M., 1 Ion 2009.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydImpact of the abolition of the prescription charge in Wales.
Hughes, D., Hughes, D. A., Alam, M. F., Cohen, D., Dunstan, F., Groves, S. & Routledge, P., 1 Ion 2009, t. O41.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydImpact of the abolition of the prescription charge in Wales.
Hughes, D., Hughes, D. A., Alam, M. F., Cohen, D., Dunstan, F., Groves, S. & Routledge, P., 1 Ion 2009.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydImpact of the abolition of the prescription charge in Wales.
Hughes, D., Hughes, D. A., Alam, M. F., Cohen, D., Dunstan, F., Groves, S. & Routledge, P., 1 Ion 2009.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydMeasurement of adherence, drug concentrations and the effectiveness of artemether-lumefantrine, chlorproguanil-dapsone or sulphadoxine-pyrimethamine in the treatment of uncomplicated malaria in Malawi.
Hughes, D., Bell, D. J., Wootton, D., Mukaka, M., Montgomery, J., Kayange, N., Chimpeni, P., Hughes, D. A., Molyneux, M. E., Ward, S. A., Winstanley, P. A. & Lalloo, D. G., 26 Awst 2009, Yn: Malaria Journal. 8, t. 204
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydNurse-led vs. conventional physician-led follow-up for patients with cancer: systematic review
Lewis, R., Neal, R. D., Williams, N. H., France, B., Wilkinson, C. E., Hendry, M., Russell, D., Russell, I., Hughes, D., Stuart, N. S. & Weller, D., 1 Ebr 2009, Yn: Journal of Advanced Nursing. 65, 4, t. 706-723
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydPatients' and healthcare professionals' views of cancer follow-up: systematic review
Lewis, R., Neal, R. D., Hendry, M., France, B., Williams, N. H., Russell, D., Hughes, D. A., Russell, I., Stuart, N. S. A., Weller, D. & Wilkinson, C., Gorff 2009, Yn: British Journal of General Practice. 59, 564, t. e248-e259
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydPharmacoeconomics: principles and relevance to the activities of drug and therapeutics committees.
Hughes, D., Hughes, D. A. & Reynolds, D. J., 1 Hyd 2009, Yn: Clinical Medicine. 9, 5, t. 490-492
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydThe economics of evergreening.
Hughes, D. & Hughes, D. A., 1 Ion 2009.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur
2008
- CyhoeddwydAll Wales Medicines Strategy Group Final Appraisal Report - Abacavir 600mg/lamivudine 300mg (Kivexa) in antiretroviral combination therapy for the treatment of Human Immunodeficiency Virus infection in adults and adolescents from 12 years of age.
Hughes, D., Hughes, D. A. & All Wales Strategy Group., [. V., 1 Ion 2008, 2008 gol. Unknown.
Allbwn ymchwil: Llyfr/Adroddiad › Adroddiad Comisiwn - CyhoeddwydAll Wales Medicines Strategy Group Final Appraisal Report - Alemtuzumab (MabCampath) for the treatment of patients with B-cell chronic lymphocytic leukaemia for whom fludarabine combination chemotherapy is not appropriate.
Hughes, D., Hughes, D. A. & All Wales Strategy Group., [. V., 1 Ion 2008, 2008 gol. Unknown.
Allbwn ymchwil: Llyfr/Adroddiad › Adroddiad Comisiwn - CyhoeddwydAll Wales Medicines Strategy Group Final Appraisal Report - Atazanavir (Reyataz) in treatment-experienced patients.
Hughes, D., Hughes, D. A. & All Wales Strategy Group., [. V., 1 Ion 2008, 2008 gol. Unknown.
Allbwn ymchwil: Llyfr/Adroddiad › Adroddiad Comisiwn - CyhoeddwydAll Wales Medicines Strategy Group Final Appraisal Report - Atazanavir (Reyataz) in treatment-naïve patients.
Hughes, D., Hughes, D. A. & All Wales Strategy Group., [. V., 1 Ion 2008, 2008 gol. Unknown.
Allbwn ymchwil: Llyfr/Adroddiad › Adroddiad Comisiwn - CyhoeddwydAll Wales Medicines Strategy Group Final Appraisal Report - Buprenorphine/naloxone (Suboxone) as substitution treatment for opioid dependence.
Hughes, D., Hughes, D. A. & All Wales Strategy Group., [. V., 1 Ion 2008, 2008 gol. Unknown.
Allbwn ymchwil: Llyfr/Adroddiad › Adroddiad Comisiwn - CyhoeddwydAll Wales Medicines Strategy Group Final Appraisal Report - Deferasirox (Exjade) for the treatment of chronic iron overload due to blood transfusions.
Hughes, D., Hughes, D. A. & All Wales Strategy Group., [. V., 1 Ion 2008, 2008 gol. Unknown.
Allbwn ymchwil: Llyfr/Adroddiad › Adroddiad Comisiwn - CyhoeddwydAll Wales Medicines Strategy Group Final Appraisal Report - Docetaxel (Taxotere) for locally advanced squamous cell carcinoma of the head and neck.
Hughes, D., Hughes, D. A. & All Wales Strategy Group., [. V., 1 Ion 2008, 2008 gol. Unknown.
Allbwn ymchwil: Llyfr/Adroddiad › Adroddiad Comisiwn - CyhoeddwydAll Wales Medicines Strategy Group Final Appraisal Report - Epoetin delta (Dynepo)
Hughes, D., Hughes, D. A. & All Wales Strategy Group., [. V., 1 Ion 2008, 2008 gol. Unknown.
Allbwn ymchwil: Llyfr/Adroddiad › Adroddiad Comisiwn - CyhoeddwydAll Wales Medicines Strategy Group Final Appraisal Report - Fondaparinux Sodium (Arixtra®) for STEMI.
Hughes, D., Hughes, D. A. & All Wales Strategy Group., [. V., 1 Ion 2008, 2008 gol. Unknown.
Allbwn ymchwil: Llyfr/Adroddiad › Adroddiad Comisiwn - CyhoeddwydAll Wales Medicines Strategy Group Final Appraisal Report - Fondaparinux Sodium (Arixtra®) for UA/NSTEMI.
Hughes, D., Hughes, D. A. & All Wales Strategy Group., [. V., 1 Ion 2008, 2008 gol. Unknown.
Allbwn ymchwil: Llyfr/Adroddiad › Adroddiad Comisiwn - CyhoeddwydAll Wales Medicines Strategy Group Final Appraisal Report - Icatibant (Firazyr) for symptomatic treatment of acute attacks of hereditary angioedema (HAE) in adults (with C1-esterase-inhibitor deficiency).
Hughes, D., Hughes, D. A. & All Wales Strategy Group., [. V., 1 Ion 2008, 2008 gol. Unknown.
Allbwn ymchwil: Llyfr/Adroddiad › Adroddiad Comisiwn - CyhoeddwydAll Wales Medicines Strategy Group Final Appraisal Report - Lenalidomide (Revlimid) for multiple myeloma.
Hughes, D., Hughes, D. A. & All Wales Strategy Group., [. V., 1 Ion 2008, 2008 gol. Unknown.
Allbwn ymchwil: Llyfr/Adroddiad › Adroddiad Comisiwn - CyhoeddwydAll Wales Medicines Strategy Group Final Appraisal Report - Pegfilgrastim (Neulasta) for the reduction in the duration of neutropenia and the incidence of febrile neutropenia in patients treated with cytotoxic chemotherapy for malignancy.
Hughes, D., Hughes, D. A. & All Wales Strategy Group., [. V., 1 Ion 2008, 2008 gol. Unknown.
Allbwn ymchwil: Llyfr/Adroddiad › Adroddiad Comisiwn - CyhoeddwydAll Wales Medicines Strategy Group Final Appraisal Report - Raltegravir (Isentress) in combination with other antiretroviral medicinal products for the treatment of human immunodeficiency virus (HIV-1) infection in treatment-experienced adult patients with evidence of HIV-1 replication despite ongoing antiretroviral therapy.
Hughes, D., Hughes, D. A. & All Wales Strategy Group., [. V., 1 Ion 2008, 2008 gol. Unknown.
Allbwn ymchwil: Llyfr/Adroddiad › Adroddiad Comisiwn - CyhoeddwydAll Wales Medicines Strategy Group Final Appraisal Report - Rufinamide (Inovelon) for the treatment of seizures associated with Lennox-Gastaut syndrome (LGS).
Hughes, D., Hughes, D. A. & All Wales Strategy Group., [. V., 1 Ion 2008, 2008 gol. Unknown.
Allbwn ymchwil: Llyfr/Adroddiad › Adroddiad Comisiwn - CyhoeddwydAll Wales Medicines Strategy Group Final Appraisal Report - Stiripentol (Diacomit) for use in conjunction with clobazam and valproate in patients with severe myoclonic epilepsy in infancy.
Hughes, D., Hughes, D. A. & All Wales Strategy Group., [. V., 1 Ion 2008, 2008 gol. Unknown.
Allbwn ymchwil: Llyfr/Adroddiad › Adroddiad Comisiwn - CyhoeddwydAll Wales Medicines Strategy Group Final Appraisal Report - Tenofovir disoproxil fumarate (Viread) for the treatment of hepatitis B.
Hughes, D., Hughes, D. A. & All Wales Strategy Group., [. V., 1 Ion 2008, 2008 gol. Unknown.
Allbwn ymchwil: Llyfr/Adroddiad › Adroddiad Comisiwn - CyhoeddwydAll Wales Medicines Strategy Group Final Appraisal Report - Teriparatide (Forsteo) for the treatment of osteoporosis in men at increased risk of fracture.
Hughes, D., Hughes, D. A. & All Wales Strategy Group., [. V., 1 Ion 2008, 2008 gol. Unknown.
Allbwn ymchwil: Llyfr/Adroddiad › Adroddiad Comisiwn - CyhoeddwydAll Wales Medicines Strategy Group Final Appraisal Report - Topotecan (Hycamtin®) for Small Cell Lung Carcinoma.
Hughes, D., Hughes, D. A. & All Wales Strategy Group., [. V., 1 Ion 2008, 2008 gol. Unknown.
Allbwn ymchwil: Llyfr/Adroddiad › Adroddiad Comisiwn - CyhoeddwydAll Wales Medicines Strategy Group Final Appraisal Report - Trabectedin (Yondelis) for advanced soft tissue sarcoma.
Hughes, D., Hughes, D. A. & All Wales Strategy Group., [. V., 1 Ion 2008, 2008 gol. Unknown.
Allbwn ymchwil: Llyfr/Adroddiad › Adroddiad Comisiwn - CyhoeddwydAll Wales Medicines Strategy Group Final Appraisal Report - Ziconotide (Prialt) for the intrathecal treatment of severe, chronic pain.
Hughes, D., Hughes, D. A. & All Wales Strategy Group., [. V., 1 Ion 2008, 2008 gol. Unknown.
Allbwn ymchwil: Llyfr/Adroddiad › Adroddiad Comisiwn - CyhoeddwydCharitable contributions to funding cancer services for children and young people in England and Wales
Hughes, D., Linck, P., Tunnage, B., Hughes, D. A. & Edwards, R. T., 1 Ion 2008, Yn: Journal of Child Health Care. 12, 2, t. 156-168
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydChiral chromatography: Costs of chiral switching.
Hughes, D. & Hughes, D. A., 1 Ion 2008, Yn: Pharmaceutical Journal. 281, t. 213
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydCost-effectiveness analysis of infliximab and adalimumab for Crohn's disease.
Hughes, D., Hughes, D. A., Bodger, K. & Kikuchi, T., 1 Ebr 2008.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydCost-effectiveness analysis of infliximab and adalimumab for Crohn's disease.
Hughes, D., Hughes, D. A., Bodger, K. & Kikuchi, T., 1 Ebr 2008.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydCost-effectiveness considerations in pharmacogenetics.
Hughes, D. & Hughes, D. A., 1 Ion 2008.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydCosts of non-compliance to antipsychotic medications among patients with schizophrenia.
Hughes, D., Hughes, D. A., Salas, M., Zuluaga, A., Cowell, W., Lebmeier, M., Vardeva, K., Pisu, M. & Shinogle, J., 1 Mai 2008.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydDevelopment of an economic model to evaluate the cost-effectiveness of rival therapies for treating Crohn’s disease.
Hughes, D., Kikuchi, T., Bodger, K. & Hughes, D. A., 1 Ion 2008, 2008 gol. Unknown.
Allbwn ymchwil: Llyfr/Adroddiad › Adroddiad Comisiwn - CyhoeddwydEconomic considerations for market access of new health technologies: A case study of pharmacogenetic testing
Hughes, D. & Hughes, D. A., 1 Chwef 2008.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydEconomic considerations for pharmacogenetic testing
Hughes, D. & Hughes, D. A., 1 Meh 2008.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydEffects of the abolition of prescription charges in Wales: A preliminary analysis
Hughes, D., Hughes, D. A., Alam, F., Cohen, D., Dunstan, F. & Routledge, P., 1 Ebr 2008.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydEffects of the abolition of prescription charges in Wales: a preliminary analysis.
Hughes, D., Cohen, D., Alam, M. F., Hughes, D. A., Dunstan, F. & Routledge, P., 1 Ion 2008, Yn: International Journal of Pharmacy Practice. 16, Supplement 1, t. A39
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydEstimation of the impact of noncompliance on pharmacokinetics: an analysis of the influence of dosing regimens
Hughes, D. & Hughes, D. A., 1 Rhag 2008, Yn: British Journal of Clinical Pharmacology. 65, 6, t. 871-878
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydFrom efficacy to cost-effectiveness: Impact of patient compliance
Hughes, D. & Hughes, D. A., 1 Chwef 2008.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydImpact of the abolition of the prescription charge in Wales
Hughes, D. & Hughes, D. A., 1 Tach 2008.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydIntegrating compliance and persistence in health economics models
Hughes, D. & Hughes, D. A., 1 Ion 2008.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydInvestigating factors influencing user choices to visit either general practioners or community pharmacists in the management of minor ailments - piloting a discrete choice experiment.
Hughes, D., Hughes, D. A., Myles, S., Longo, M. & Lisles, C., 1 Ion 2008, 2008 gol. Unknown.
Allbwn ymchwil: Llyfr/Adroddiad › Adroddiad Comisiwn - CyhoeddwydInvestigating factors influencing user choices to visit either general practitioners or community pharmacists in the management of minor ailments – piloting a discrete choice experiment
Hughes, D., Hughes, D. A., Myles, S., Longo, M. & Lisles, C., 1 Maw 2008
Allbwn ymchwil: Ffurf annhestunol › Safe Gwe / Cyhoeddiad Gwe - CyhoeddwydMedicines concordance and game theory.
Hughes, D. & Hughes, D. A., 1 Hyd 2008, Yn: British Journal of Clinical Pharmacology. 66, 4, t. 577
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydMethodological Issues in the literature on costs of non-compliance in chronic diseases.
Hughes, D., Salas, M., Zuluaga, A., Hughes, D. A., Cowell, W., Lebmeier, M., Vardeva, K., Pisu, M. & Shinogle, J., 1 Tach 2008, Yn: Value in Health. 11, 6, t. A571-A572
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydMethodological issues in the literature on costs of non-compliance in chronic diseases
Hughes, D., Salas, M., Zuluaga, A., Hughes, D. A., Cowell, W., Lebmeie, M., Vardeva, K., Pisu, M. & Shinogle, J., 1 Tach 2008.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydPublic health interventions to promote well-being in people aged 65 and over: systematic review of effectiveness and cost-effectiveness.
Hughes, D., Linck, P. G., Windle, G., Hughes, D. A., Linck, P., Russell, I. T., Morgan, R., Woods, R. T., Burholt, V., Edwards, R. T., Reeves, C. & Yeo, S. T., 1 Ion 2008, 2008 gol. Unknown.
Allbwn ymchwil: Llyfr/Adroddiad › Adroddiad Comisiwn - CyhoeddwydPublic health interventions to promote well-being in people aged 65 and over: systematic review of effectiveness and cost-effectiveness: Evidence Tables.
Hughes, D., Linck, P. G., Windle, G., Linck, P., Morgan, R., Hughes, D. A., Burholt, V., Reeves, C., Yeo, S. T., Woods, R. T., Edwards, R. T. & Russell, I. T., 1 Ion 2008, 2008 gol. Unknown.
Allbwn ymchwil: Llyfr/Adroddiad › Adroddiad Comisiwn - CyhoeddwydStatistical comments are unfounded.
Hughes, D., Hughes, D. A., Cowell, W., Koncz, T. & Cramer, J., 1 Maw 2008, Yn: Value in Health. 11, 2, t. 346
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydThe all wales medicines strategy group: assessments and appraisals
Hughes, D. & Hughes, D. A., 1 Tach 2008.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydThe cost-effectiveness of biological therapies for Crohn's disease: Markov cohort analyses incorporating UK patient-level cost data
Hughes, D., Bodger, K., Kikuchi, T. & Hughes, D. A., 1 Maw 2008.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydThe cost-effectiveness of biological therapies for Crohn's disease: markov cohot analyses incorporating UK patient-level cost data
Hughes, D., Hughes, D. A., Bodger, K. & Kikuchi, T., 1 Mai 2008.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydUnderstanding medication compliance and persistence from an economics perspective
Hughes, D., Elliot, R. A., Shinogle, J. A., Peele, P., Bhosle, M. & Hughes, D. A., 1 Ion 2008, Yn: Value in Health. 11, 4, t. 600-610
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
2007
- CyhoeddwydA Global Survey of Antibiotic Leftovers in the Outpatient Setting.
Hughes, D., Kardas, P., Pechere, J. C., Hughes, D. A. & Cornaglia, G., 1 Rhag 2007, Yn: International Journal of Antimicrobial Agents. 30, 6, t. 530-536
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydA parenting programme for children at risk of developing conduct disorder: A cost-effectiveness analysis
Hughes, D., Edwards, R. T., Ceilleachair, A., Bywater, T., Hughes, D. A. & Hutchings, J., 1 Mai 2007.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydA prototype agent-based model of antimalarial drug compliance
Hughes, D., McKean, J., Rahlf, S., Shorter, H., Barnish, G., Paton, R., McBurney, P., Hughes, D. A. & Hastings, I., 1 Awst 2007.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydAWMSG criteria for appraising new medicines.
Hughes, D. & Hughes, D. A., 1 Ion 2007, 2007 gol. Unknown.
Allbwn ymchwil: Llyfr/Adroddiad › Adroddiad Comisiwn - CyhoeddwydAdherence with HAART: pharmacoeconomic considerations
Hughes, D. & Hughes, D. A., 1 Meh 2007.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydAdverse drug reactions in economic evaluations
Hughes, D. & Hughes, D. A., 1 Maw 2007.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydAdverse drug reactions in economic evaluations
Hughes, D. & Hughes, D. A., 1 Gorff 2007.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydAdverse drug reactions in economic evaluations
Hughes, D. & Hughes, D. A., 1 Ion 2007, Yn: Value in Health. 10, 3, t. A109
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydAdverse drug reactions: analysis by regulatory authorities and by economists
Hughes, D. & Hughes, D. A., 1 Ebr 2007.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydAll Wales Medicines Strategy Group Final Appraisal Report - Emtricitabine/tenofovir DF (Truvada)
Hughes, D., Hughes, D. A. & All Wales Strategy Group., [. V., 1 Ion 2007, 2007 gol. Unknown.
Allbwn ymchwil: Llyfr/Adroddiad › Adroddiad Comisiwn - CyhoeddwydAll Wales Medicines Strategy Group Final Appraisal Report – Clofarabine (Evoltra)
Hughes, D., Hughes, D. A. & All Wales Strategy Group., [. V., 1 Ion 2007, 2007 gol. Unknown.
Allbwn ymchwil: Llyfr/Adroddiad › Adroddiad Comisiwn - CyhoeddwydAll Wales Medicines Strategy Group Final Appraisal Report – Co-careldopa intestinal gel (Duodopa).
Hughes, D., Hughes, D. A. & All Wales Strategy Group., [. V., 1 Ion 2007, 2007 gol. Unknown.
Allbwn ymchwil: Llyfr/Adroddiad › Adroddiad Comisiwn - CyhoeddwydAll Wales Medicines Strategy Group Final Appraisal Report – Darunavir (Prezista)
Hughes, D., Hughes, D. A. & All Wales Strategy Group., [. V., 1 Ion 2007, 2007 gol. Unknown.
Allbwn ymchwil: Llyfr/Adroddiad › Adroddiad Comisiwn - CyhoeddwydAll Wales Medicines Strategy Group Final Appraisal Report – Dasatinib (Sprycel®) Chronic, accelerated or blast phase CML.
Hughes, D., Hughes, D. A. & All Wales Strategy Group., [. V., 1 Ion 2007, 2007 gol. Unknown.
Allbwn ymchwil: Llyfr/Adroddiad › Adroddiad Comisiwn - CyhoeddwydAll Wales Medicines Strategy Group Final Appraisal Report – Dasatinib (Sprycel®) Lymphoid blast CML and PH+ ALL.
Hughes, D., Hughes, D. A. & All Wales Strategy Group., [. V., 1 Ion 2007, 2007 gol. Unknown.
Allbwn ymchwil: Llyfr/Adroddiad › Adroddiad Comisiwn - CyhoeddwydAll Wales Medicines Strategy Group Final Appraisal Report – Dexrazoxane (Savene)
Hughes, D., Hughes, D. A. & All Wales Strategy Group., [. V., 1 Ion 2007, 2007 gol. Unknown.
Allbwn ymchwil: Llyfr/Adroddiad › Adroddiad Comisiwn - CyhoeddwydAll Wales Medicines Strategy Group Final Appraisal Report – Emtricitabine (Emtriva)
Hughes, D., Hughes, D. A. & All Wales Strategy Group., [. V., 1 Ion 2007, 2007 gol. Unknown.
Allbwn ymchwil: Llyfr/Adroddiad › Adroddiad Comisiwn - CyhoeddwydAll Wales Medicines Strategy Group Final Appraisal Report – Idursulfase (Elaprase)
Hughes, D., Hughes, D. A. & All Wales Strategy Group., [. V., 1 Ion 2007, 2007 gol. Unknown.
Allbwn ymchwil: Llyfr/Adroddiad › Adroddiad Comisiwn - CyhoeddwydAll Wales Medicines Strategy Group Final Appraisal Report – Parathyroid hormone (Preotact)
Hughes, D., Hughes, D. A. & All Wales Strategy Group., [. V., 1 Ion 2007, 2007 gol. Unknown.
Allbwn ymchwil: Llyfr/Adroddiad › Adroddiad Comisiwn - CyhoeddwydAll Wales Medicines Strategy Group Final Appraisal Report – Tipranavir (Aptivus).
Hughes, D., Hughes, D. A. & All Wales Strategy Group., [. V., 1 Ion 2007, 2007 gol. Unknown.
Allbwn ymchwil: Llyfr/Adroddiad › Adroddiad Comisiwn - CyhoeddwydAll Wales Medicines Strategy Group Final Assessment Report – Agalsidase alfa (Replagal)
Hughes, D., Hughes, D. A. & All Wales Strategy Group., [. V., 1 Ion 2007, 2007 gol. Unknown.
Allbwn ymchwil: Llyfr/Adroddiad › Adroddiad Comisiwn - CyhoeddwydAssessing the association between compliance and therapeutic failure for antiretroviral drugs in HIV positive patients
Hughes, D., 1 Maw 2007.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydAssessing the association between compliance and therapeutic failure for antiretroviral drugs in HIV positive patients
Hughes, D. & Hughes, D. A., 1 Ion 2007, Yn: Value in Health. 10, 3, t. A171
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydAssessing the association between compliance and therapeutic failure for antiretroviral drugs in HIV positive patients
Hughes, D. & Hughes, D. A., 1 Mai 2007.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydBiological agents for the management of Crohn's disease in adults: A systematic review, meta-analysis and multiples treatment comparison
Hughes, D., Hughes, D. A., Kikuchi, T. & Bodger, K., 1 Ion 2007, Yn: Value in Health. 10, 3, t. A147
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydBiological agents for the management of Crohn's disease in adults: a systematic review, meta-analysis and multiple treatment comparison
Hughes, D., Hughes, D. A., Kikuchi, T. & Bodger, K., 1 Mai 2007.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydCost of non-compliance and non-persistence with medications for diabetes mellitus
Hughes, D., Salas, M., Hughes, D. A., Lebmeier, M. & Vardeva, K., 1 Awst 2007.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydCurrent assessment of risk-benefit by regulators: Is it time to introduce decision analyses?
Hughes, D., Hughes, D. A., Pirmohamed, M. & Bayoumi, A., 1 Awst 2007.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydCurrent assessment of risk-benefit by regulators: is it time to introduce decision analyses?
Hughes, D., Hughes, D. A., Bayoumi, A. M. & Pirmohamed, M., 1 Awst 2007, Yn: Clinical Pharmacology and Therapeutics. 82, 2, t. 123-127
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydEconomic evaluation of steroid injections (methylprednisolone) in the treatment of Morton's neuroma: patient-blind randomised trial
Hughes, D., Thomson, C., Beggs, I., Martin, D., McCaldin, D., Russell, D., Edwards, R. T., Hughes, D. A., Yeo, S. T., Russell, I. T. & Gibson, T. N., 1 Maw 2007.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydFactors influencing user choices to visit either general practitioners or community pharmacists for minor ailments – a discrete choice experiment
Hughes, D., Hughes, D. A., Myles, S., Longo, M., Lisles, C. & Hood, K., 1 Mai 2007.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydFactors influencing user choices to visit either general practitioners or community pharmacists for minor ailments – a discrete choice experiment
Hughes, D., Hughes, D. A., Myles, S., Longo, M., Lisles, C. & Hood, K., 1 Ion 2007, Yn: Value in Health. 10, 3, t. A23
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydFalls and hip-fractures: A cost-effectiveness analysis of risk assessment and interventions for community-dwelling older people
Hughes, D., Gwynne, D., Hughes, D. A. & Edwards, R. T., 1 Maw 2007.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydFeasibility, validity and reliability of the Welsh EQ-5D health status questionnaire
Hughes, D. & Hughes, D. A., 1 Mai 2007.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydFeasibility, validity and reliability of the Welsh EQ-5D health status questionnaire
Hughes, D., 1 Maw 2007.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydFeasibility, validity and reliability of the Welsh version of the EQ-5D health status questionnaire.
Hughes, D. & Hughes, D. A., 1 Hyd 2007, Yn: Quality of Life Research. 16, 8, t. 1419-1423
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydFeasibility, validity, and reliability of the Welsh version of the EQ-5D health status questionnaire
Hughes, D. & Hughes, D. A., 1 Ion 2007, Yn: Value in Health. 10, 3, t. A189
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydFolate Augmentation of Treatment – Evaluation for Depression (FolATED): protocol of a randomised controlled trial.
Russell, I. T., Slegg, G. P., Roberts, S. H., Bedson, E., Hughes, D., Lloyd, K., Moat, S., Pirmohamed, M., Slegg, G., Tranter, R., Whitaker, R., Wilkinson, C. & Russell, I., 15 Tach 2007, Yn: BMC Psychiatry. 7, 1, t. 65
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydFollow-up of cancer patients in primary care versus secondary care: systematic review.
Hughes, D., Lewis, R., Neal, R., Williams, N., France, B., Wilkinson, C., Hendry, M., Russell, D., Hughes, D. A., Russell, I. T., Stuart, N. S. & Weller, D., 1 Ion 2007, 2007 gol. Unknown.
Allbwn ymchwil: Llyfr/Adroddiad › Adroddiad Comisiwn - CyhoeddwydImpact of the abolition of prescription charges in Wales: a multi-level modelling approach with application to time series dispensed rate data
Hughes, D., Alam, F., Myles, S., Hughes, D. A., Dunstan, F., Routledge, P. & Cohen, D., 1 Medi 2007.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydInterventions that enhance medication compliance and persistence: Theoretical grounding, and economic assessment
Hughes, D., Hughes, D. A., Gwadry Sridhar, F., Elliott, R. & Cowell, W., 1 Hyd 2007.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydMethods for integrating medication compliance and persistence in pharmacoeconomic evaluations.
Hughes, D., Hughes, D. A., Cowell, W., Koncz, T. & Cramer, J., 1 Tach 2007, Yn: Value in Health. 10, 6, t. 498-509
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydNon-compliance with antibiotic therapy for acute community infections: A global survey.
Hughes, D., Pechere, J. C., Hughes, D. A., Kardas, P. & Cornaglia, G., 1 Maw 2007, Yn: International Journal of Antimicrobial Agents. 29, 3, t. 245-253
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydOrphan drug treatments: economic considerations
Hughes, D. & Hughes, D. A., 1 Tach 2007.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydParenting programme for parents of children at risk of developing conduct disorder: cost effectiveness analysis.
Bywater, T. J., Hutchings, J. M., Hughes, D., Edwards, R. T., Ceilleachair, A., Bywater, T., Hughes, D. A. & Hutchings, J., 31 Maw 2007, Yn: British Medical Journal. 334, 7595, t. 682-685
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydPharmacoeconomic evaluations in Ireland, Scotland and Wales: A Celtic perspective on pharmaceutical assessment
Hughes, D., Hughes, D. A., Drummond, M., Tolley, K. & Ryan, M., 1 Hyd 2007.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydPolicy on ultra-orphan drugs.
Hughes, D. & Hughes, D. A., 1 Ion 2007, 2007 gol. Unknown.
Allbwn ymchwil: Llyfr/Adroddiad › Adroddiad Comisiwn - CyhoeddwydPopulation pharmacokinetics of warfarin: Intermin analysis of the Liverpool pharmacogenetic prospective cohort study
Hughes, D., Matthews, I., Aarons, L., Al-Zubiedi, S., Hatch, E., Lane, S., Williamson, P., Kamali, F., Hughes, D. A. & Pirmohamed, M., 1 Tach 2007.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydPublic health interventions to promote mental well-being in people aged 65 and over: systematic review of effectiveness and cost-effectiveness.
Hughes, D., Windle, G., Hughes, D. A., Linck, P., Morgan, R., Burholt, V., Edwards, R. T., Reeves, C., Yeo, S. T., Woods, R. T. & Russell, I. T., 1 Ion 2007, 2007 gol. Unknown.
Allbwn ymchwil: Llyfr/Adroddiad › Adroddiad Comisiwn - CyhoeddwydPublic meetings of the NICE appraisals committee
Hughes, D. & Hughes, D. A., 1 Rhag 2007.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydQuantitative risk-benefit analysis
Hughes, D. & Hughes, D. A., 1 Mai 2007.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydSystematic review of follow-up of cancer in primary care verses secondary care: findings for breast and lung cancer
Hughes, D., Lewis, R., Neal, R. D., France, B., Williams, N. H., Wilkinson, C., Russell, I. T., Russell, D., Hughes, D. A., Stuart, N. S. & Weller, D., 1 Maw 2007.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydThe assessment, determinants & economics of medication compliance & persistence
Hughes, D., Hughes, D. A., Gwadry Sridhar, F. & Elliott, R., 1 Hyd 2007.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydThe effect of compliance upon clinical effectiveness of chlorproguanil-dapsone (CD) and artemether-lumefantrine (AL) when compared to sulfadoxine-pyrimethamine (SP) for the treatment of uncomplicated falcipaum malaria in Malawi - a randomised controlled trial
Hughes, D., Bell, D. J., Wootton, D., Mukaka, M., Montgomery, J., Kayange, N., Chimpeni, P., Zijlstra, E., Hughes D.A., [. V., Molyneux M.E.*, [. V., Ward, S. A., Winstanley, P. A. & Lalloo, D. G., 1 Tach 2007.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydThe pharmacokinetic profile of Warfarn: a systematic review
Hughes, D., Al-Zubiedi S.*, [. V., Hughes D.A., [. V. & Pirmohamed, M., 1 Rhag 2007.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydWarfarin pharmacogenetics: Economic considerations.
Hughes, D., Hughes, D. A. & Pirmohamed, M., 1 Ion 2007, Yn: Pharmacoeconomics. 25, 11, t. 899-902
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydWhat determines which interventions improve compliance, and do they improve health outcomes in a cost-effective manner?
Hughes, D., Hughes, D. A., LaFleur.*, [. V., Salas, M. & Shinogle, J., 1 Mai 2007.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydWhen drugs don't work - Economic assessment of enhancing compliance with interventions supported by electronic monitoring devices.
Hughes, D. & Hughes, D. A., 1 Ion 2007, Yn: Pharmacoeconomics. 25, 8, t. 621-635
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
2006
- CyhoeddwydBack to basics: what is the relationship between dose and duration of drug action?
Hughes, D. & Hughes, D. A., 1 Mai 2006.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydBeyond registration: measuring the public health potential of new treatments for Malaria in Africa.
Hughes, D., Lang, T., Hughes, D. A., Kanyok, T., Kengeya-Kayondo, J., Marsh, V., Haaland, A., Pirmohamed, M. & Winstanley, P., 1 Ion 2006, Yn: Lancet Infectious Diseases. 6, 1, t. 46-52
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydClinical and econnomic importance of completion of therapy in the treatment of LRTIs
Hughes, D. & Hughes, D. A., 1 Medi 2006.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydEliciting patients' preferences using a discrete choice experiment questionnaire: the role played by qualitative data in questionnaire design
Hughes, D., Longo, M., Hughes, D. A., Myles, S. & Lisles, C., 1 Maw 2006.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydHealth and economic outcomes: Why compliance matters
Hughes, D. & Hughes, D. A., 1 Ebr 2006.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydHealth economic aspects of patient non-compliance
Hughes, D., Hughes, D. A., Davies, M. (Golygydd) & Kermani, F. (Golygydd), 1 Ion 2006, Patient Compliance: Sweetening the Pill. 2006 gol. Gower Publishing, t. 23-40
Allbwn ymchwil: Pennod mewn Llyfr/Adroddiad/Trafodion Cynhadledd › Pennod - CyhoeddwydImproving Outcomes for People with Brain and Other CNS Tumours: Analysis of the Potential Economic Impact of the Guidance.
Hughes, D., Linck, P., Priedane, E., Hughes, D. A. & Edwards, R. T., 1 Ion 2006, 2006 gol. Unknown.
Allbwn ymchwil: Llyfr/Adroddiad › Adroddiad Comisiwn - CyhoeddwydImproving Outcomes for People with Sarcoma: Analysis of the Potential Economic Impact of the Guidance.
Hughes, D., Linck, P., Hughes, D. A. & Edwards, R. T., 1 Ion 2006, 2006 gol. Unknown.
Allbwn ymchwil: Llyfr/Adroddiad › Adroddiad Comisiwn - CyhoeddwydImproving Outcomes for People with Skin Tumours including Melanoma: Analysis of the Potential Economic Impact of the Guidance.
Hughes, D., Linck, P., Hughes, D. A. & Edwards, R. T., 21 Chwef 2006, Unknown.
Allbwn ymchwil: Llyfr/Adroddiad › Adroddiad Comisiwn - CyhoeddwydInvestigating factors influencing user choices to visit either general practitioners or community pharmacists in the management of minor ailments
Hughes, D. & Hughes, D. A., 1 Mai 2006.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydInvestigating factors influencing user choices to visit either general practitioners or community pharmacists in the management of minor ailments - piloting a discrete choice experiment
Hughes, D., Myles, S., Hughes, D. A., Longo, M. & Lisles, C., 1 Meh 2006.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydLess is more: Medicines that require less frequent administration improve adherence, but are they better?
Hughes, D. & Hughes, D. A., 1 Ion 2006, Yn: Pharmacoeconomics. 24, 3, t. 211-213
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydOrphan drugs revisited: author's response.
Hughes, D. & Hughes, D. A., 1 Mai 2006, Yn: Quarterly Journal of Medicine. 99, 5, t. 350-351
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydPhyschiatrist prescribing preferences and attitudes toward promotion
Hughes, D., Menkes, D., Davies, R. & Hughes, D. A., 1 Ebr 2006.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydPopulation pharmacokinetic and pharmacodynamic modelling of the antimalarial chemotherapy chlorproguanil/dapsone.
Simpson, J. A., Hughes, D., Manyando, C., Bojang, K., Aarons, L., Winstanley, P., Edwards, G., Watkins, W. A. & Ward, S., 1 Maw 2006, Yn: British Journal of Clinical Pharmacology. 61, 3, t. 289-300
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydPrescription fee exemption research study
Hughes, D., Myles, S., Hughes, D. A., Routledge, P. & Wales, D. F., 1 Meh 2006.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydPublic funding of drugs for orphan diseases
Hughes, D. & Hughes, D. A., 1 Ion 2006.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydRationing of drugs for rare diseases
Hughes, D. & Hughes, D. A., 1 Ebr 2006.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydRationing of drugs for rare diseases.
Hughes, D. & Hughes, D. A., 1 Ion 2006, Yn: Pharmacoeconomics. 24, 4, t. 315-316
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydUltra-long acting pharmaceuticals: Do they result in better outcomes, and at an acceptable cost?
Hughes, D. & Hughes, D. A., 1 Tach 2006.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur
2005
- CyhoeddwydCisplatin plus vinorelbine or gemcitabine in patients with advanced non-small cell lung cancer: Pharmacoeconomic considerations.
Hughes, D. & Hughes, D. A., 1 Gorff 2005, Yn: European Journal of Cancer. 41, 11, t. 1655
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydCost minimization of on-demand maintenance therapy with proton pump inhibitors in nonerosive gastroesophageal reflux disease.
Hughes, D., Hughes, D. A., Marchetti, M. & Colombo, G., 1 Chwef 2005, Yn: Expert Review of Pharmacoeconomics and Outcomes Research. 5, 1, t. 29-38
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydDrugs for exceptionally rare diseases: do they deserve special status for funding?
Hughes, D., Tunnage, B. & Yeo, S. T., 1 Tach 2005, Yn: QJM - An International Journal of Medicine. 98, 11, t. 829-836
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydEconomic analysis of on-demand maintenance therapy with proton pump inhibitors in patients with non-erosive reflux disease.
Hughes, D., Hughes, D. A., Bodger, K., Bytzer, P., De Herdt, D. & Dubois, D., 1 Ion 2005, Yn: Pharmacoeconomics. 23, 10, t. 1031-1041
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydEmpirical analysis of the relationship between dose and duration of drug action
Hughes, D. & Hughes, D. A., 1 Meh 2005.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydImproving Outcomes in Children and Young People with Cancer: Analysis of the Potential Economic Impact of the Guidance.
Hughes, D., Linck, P., Tunnage, B., Hughes, D. A. & Edwards, R. T., 1 Ion 2005, 2005 gol. Unknown.
Allbwn ymchwil: Llyfr/Adroddiad › Adroddiad Comisiwn - CyhoeddwydIncorporating measures of compliance and persistence in pharmacoeconomic evaluations
Hughes, D., Hughes, D. A. & Cowell, W., 1 Tach 2005.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydInternationalisation of cost-effectiveness model for on-demand use of proton pump inhibitors - Sweden.
Hughes, D. & Hughes, D. A., 1 Ion 2005, 2005 gol. Unknown.
Allbwn ymchwil: Llyfr/Adroddiad › Adroddiad Comisiwn - CyhoeddwydPharmacokinetics, patient compliance and pharmaeconomics
Hughes, D. & Hughes, D. A., 1 Meh 2005.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydPublic funding of drugs for orphan diseases
Hughes, D. & Hughes, D. A., 11 Tach 2005, Yn: Value in Health. 8, 6, t. A192
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydPublic funding of drugs for orphan diseases
Hughes, D. & Hughes, D. A., 1 Tach 2005.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydPublic funding of drugs for orphan diseases
Hughes, D. & Hughes, D. A., 1 Tach 2005.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydPublic funding of drugs for orphan diseases
Hughes, D. & Hughes, D. A., 1 Gorff 2005.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydTrends and influences on use of antidiabetic drugs in England, 1992-2003.
Walley, T., Hughes, D. & Kendall, H., 1 Tach 2005, Yn: Pharmacoepidemiology and Drug Safety. 14, 11, t. 769-773
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydWelsh Health Economics Network (WHEN): Scoping Report.
Hughes, D., Farr, A., O Ceilleachair, A., Cohen, D., Hughes, D. A. & Phillips, C., 1 Ion 2005, 2005 gol. Unknown.
Allbwn ymchwil: Llyfr/Adroddiad › Adroddiad Comisiwn
2004
- CyhoeddwydA single centre open phase IV study to evaluate the safety and tolerability of chlorproguanil-dapsone when dosed by defined height bands
Hughes, D., Makanga, M., Winstanley, P. & Hughes, D. A., 1 Tach 2004.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydApproaches to pharmacoeconomic analysis
Hughes, D., Hughes, D. A., Walley, T. (Golygydd), Haycox, A. (Golygydd), Boland, A. (Golygydd) & Breckenridge, A. (Golygydd), 1 Ion 2004, Pharmacoeconomics. 2004 gol. Adis International, t. 101-126
Allbwn ymchwil: Pennod mewn Llyfr/Adroddiad/Trafodion Cynhadledd › Pennod - CyhoeddwydClinical Pharmacology: Special safety considerations in drug development and pharmacovigilance.
Hughes, D., Atuah, K. N., Hughes, D. A. & Pirmohamed, M., 1 Ion 2004, Yn: Drug Safety. 27, 8, t. 535-554
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydCost minimization of on-demand maintenance therapy with proton pump inhibitors in nonerosive gastroesophageal reflux disease
Hughes, D. & Hughes, D. A., 1 Tach 2004, Yn: Value in Health. 7, 6, t. 753
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydCost-effectiveness analysis of HLA B*5701 genotyping in preventing abacavir hypersensitivity
Hughes, D., Hughes, D. A., Vilar, F. J., Ward, C. C., Alfirevic, A., Park, B. K. & Pirmohamed, M., 1 Meh 2004, Yn: Pharmacogenetics. 14, 6, t. 335-342
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydCost-effectiveness analysis of extended-release formulations of oxybutynin and tolterodine for the management of urge incontinence.
Hughes, D., Hughes, D. A. & Dubois, D., 1 Ion 2004, Yn: Pharmacoeconomics. 22, 16, t. 1047-1059
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydEconomic evaluation of on-demand maintenance therapy with proton pump inhibitors in patients with symptomatic gastroesophageal reflux disease - a Monte-Carlo analysis for Italy
Hughes, D., Hughes, D. A., Marchetti, M. & Colombo, G., 1 Hyd 2004.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydFrom efficacy to effectiveness and cost-effectiveness: modelling possibilities
Hughes, D. & Hughes, D. A., 1 Tach 2004.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydHLA-B*5701 and abacavir hypersensitivity - Reply.
Hughes, D., Hughes, D. A., Park, B. K. & Pirmohamed, M., 1 Tach 2004, Yn: Pharmacogenetics. 14, 11, t. 784
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydInternationalisation of cost-effectiveness model for on-demand use of proton pump inhibitors - Belgium.
Hughes, D. & Hughes, D. A., 1 Ion 2004, 2004 gol. Unknown.
Allbwn ymchwil: Llyfr/Adroddiad › Adroddiad Comisiwn - CyhoeddwydIntroduction to pharmaeconomics
Hughes, D. & Hughes, D. A., 1 Gorff 2004.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydModelling in health economics
Hughes, D., Hughes, D. A., Walley, T. (Golygydd), Haycox, A. (Golygydd), Boland, A. (Golygydd) & Breckenridge, A. (Golygydd), 1 Ion 2004, Pharmacoeconomics. 2004 gol. Adis International, t. 141-154
Allbwn ymchwil: Pennod mewn Llyfr/Adroddiad/Trafodion Cynhadledd › Pennod - CyhoeddwydPatient compliance and persistence with prescribed medication: Measurement and health economic impact
Hughes, D., Koncz, T., Hughes, D. A., Cleemput, I. & Annemans, L., 1 Mai 2004.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydPharmacoeconomic models that incorporate non-compliance
Hughes, D. & Hughes, D. A., 1 Gorff 2004.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydPharmacoeconomics appraisals by the all Wales medicines strategy group
Hughes, D. & Hughes, D. A., 1 Gorff 2004.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydPharmacoeconomics in Wales: functions of the all Wales medicines strategy group
Hughes, D. & Hughes, D. A., 1 Ebr 2004.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydPharmacoeconomics of pharmacogenetic testing: azathioprine
Hughes, D., McAllister, R. & Hughes, D. A., 1 Ebr 2004.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydThe difference between effectiveness and efficacy of antimalarial drugs in Kenya.
Hughes, D., Amin, A. A., Hughes, D. A., Marsh, V., Abuya, T. O., Kokwaro, G. O., Winstanley, P. A., Ochala, S. A. & Snow, R. W., 1 Medi 2004, Yn: Tropical Medicine and International Health. 9, 9, t. 967-974
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydThe future challenges
Hughes, D., Hughes, D. A., Walley, T. (Golygydd), Haycox, A. (Golygydd), Boland, A. (Golygydd) & Breckenridge, A. (Golygydd), 1 Ion 2004, Pharmacoeconomics. 2004 gol. Adis International, t. 167-174
Allbwn ymchwil: Pennod mewn Llyfr/Adroddiad/Trafodion Cynhadledd › Pennod
2003
- CyhoeddwydAbacavir hypersensitivity: Is pre-prescription genotyping cost-effective?
Hughes, D. & Hughes, D. A., 1 Meh 2003.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydAbacavir hypersensitivity: Is pre-prescription genotyping cost-effective?
Hughes, D., Hughes, D. A. & Pirmohamed, M., 1 Medi 2003.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydAbacavir hypersensitivity: Is pre-prescription genotyping cost-effective?
Hughes, D. & Hughes, D. A., 1 Mai 2003.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydAbacavir hypersensitivity: Is pre-prescription genotyping cost-effective?
Hughes, D., Hughes, D. A. & Pirmohamed, M., 1 Tach 2003, Yn: Value in Health. 6, 6, t. 749
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydAbacavir hypersensitivity: Is pre-prescription genotyping cost-effective?
Hughes, D., Hughes, D. A. & Pirmohamed, M., 1 Tach 2003.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydCost-utility analysis of on demand rabeprazole and esomeprazole for symptomatic gastro oesophageal reflux disease
Hughes, D., Hughes, D. A. & Dubois, D., 1 Tach 2003, Yn: Value in Health. 6, 6, t. 613
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydCost-utility analysis of on-demand rabeprazole and esomeprazole for non-erosive reflux disease
Hughes, D. & Hughes, D. A., 1 Tach 2003.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydCost-utility analysis of on-demand rabeprazole and esomeprazole for non-erosive reflux disease
Hughes, D. & Hughes, D. A., 1 Tach 2003.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydDrug compliance and pharmaceconomics
Hughes, D. & Hughes, D. A., 1 Rhag 2003.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydModelling changes in first line antimalarial therapy
Hughes, D. & Hughes, D. A., 1 Medi 2003.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydPredicting "real world" effectiveness by integrating adherence with pharmacodynamic modelling.
Hughes, D., Hughes, D. A. & Walley, T., 1 Gorff 2003, Yn: Clinical Pharmacology and Therapeutics. 74, 1, t. 1-8
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydUse of PK-PD modelling to predict the impact of non-compliance
Hughes, D. & Hughes, D. A., 1 Tach 2003.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur
2002
- CyhoeddwydAccurate and practical dosing of African populations using a height, weight and age model designed for lapdap
Hughes, D., Hughes, D. A. & Bagust, A., 1 Tach 2002.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydEconomic evaluation during early (phase II) trials
Hughes, D. & Hughes, D. A., 1 Tach 2002.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydEconomic impact of poor compliance with pharmaceuticals.
Hughes, D. & Hughes, D. A., 1 Awst 2002, Yn: Expert Review of Pharmacoeconomics and Outcomes Research. 2, 4, t. 327-335
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydFrom efficacy to cost-effectiveness: accounting for non-compliance in pharmacoeconomics
Hughes, D. & Hughes, D. A., 1 Mai 2002.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydImpact of non-compliance on the cost-effectiveness of pharmaceuticals
Hughes, D. & Hughes, D. A., 1 Tach 2002.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydImpact of non-compliance on the therapeutic coverage of oxybutynin – comparison of once- and twice-daily oral formulations.
Hughes, D. & Hughes, D. A., 1 Ion 2002, 2002 gol. Unknown.
Allbwn ymchwil: Llyfr/Adroddiad › Adroddiad Comisiwn - CyhoeddwydImpact of non-compliance on the therapeutic coverage of risperidone – comparison of long acting injectible with oral formulations.
Hughes, D. & Hughes, D. A., 1 Ion 2002, 2002 gol. Unknown.
Allbwn ymchwil: Llyfr/Adroddiad › Adroddiad Comisiwn - CyhoeddwydPatient compliance and pharmacoeconomics
Hughes, D. & Hughes, D. A., 1 Tach 2002.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydThe population pharmacokinetics of lapdap
Hughes, D., Ward, S., Simpson, J., Aarons, L., Szwandt, S. & Hughes, D. A., 1 Tach 2002.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur
2001
- CyhoeddwydA review of economic models for second-line chemotherapy in the management of advanced, metastatic breast cancer.
Hughes, D. & Hughes, D. A., 1 Ion 2001, 2001 gol. Unknown.
Allbwn ymchwil: Llyfr/Adroddiad › Adroddiad Comisiwn - CyhoeddwydAccounting for non-compliance in pharmacoeconomic evaluations.
Hughes, D., Hughes, D. A., Bagust, A., Haycox, A. & Walley, T., 1 Ion 2001, Yn: Pharmacoeconomics. 19, 12, t. 1185-1197
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydEconomic evaluations during early (Phase II) drug development: A role for clinical trial simulations.
Hughes, D., Hughes, D. A. & Walley, T., 1 Ion 2001, Yn: Pharmacoeconomics. 19, 11, t. 1069-1077
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydImpact of non-compliance on the clinical and cost-effectiveness of statins
Hughes, D. & Hughes, D. A., 1 Tach 2001.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydImpact of non-compliance on the cost-effectiveness of statin therapy
Hughes, D., Hughes, D. A. & Bagust, A., 1 Medi 2001, Yn: Value in Health. 4, 6, t. 489
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydPatient compliance and pharmacoeconomics
Hughes, D. & Hughes, D. A., 1 Hyd 2001.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydPharmacokinetic-Pharmacodynamic modelling of Lapdap (CPG-DDS) combination.
Hughes, D., Hughes, D. A., Watkins, B. & Winstanley, P., 1 Ion 2001, 2001 gol. Unknown.
Allbwn ymchwil: Llyfr/Adroddiad › Adroddiad Comisiwn - CyhoeddwydPharmacometric analysis of duration of drug action: implications for improved forgiveness to medication non-compliance
Hughes, D., Hughes, D. A. & Walley, T., 1 Medi 2001.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydThe impact of non-compliance on the cost-effectiveness of pharmaceuticals: A review of the literature.
Hughes, D., Hughes, D. A., Bagust, A., Haycox, A. & Walley, T., 1 Hyd 2001, Yn: Health Economics. 10, 7, t. 601-615
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid - CyhoeddwydThe influence of non-compliance on the effectiveness and cost-effectiveness of drug therapies.
Hughes, D. & Hughes, D. A., 1 Ion 2001, 2001 gol. Unknown.
Allbwn ymchwil: Llyfr/Adroddiad › Adroddiad Comisiwn
2000
- CyhoeddwydPragmatic trials - design features and implications for clinical decision making
Hughes, D., Urdahl, H., Hughes, D. A. & Freemantle, N., 1 Awst 2000.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydThe influence of non-compliance on the effectiveness and cost-effectiveness of drug therapies
Hughes, D., Hughes, D. A., Bagust, A., Haycox, A. & Walley, T., 1 Tach 2000.
Allbwn ymchwil: Cyfraniad at gynhadledd › Papur - CyhoeddwydThe influence of non-compliance on the effectiveness and cost-effectiveness of drug therapies
Hughes, D., Hughes, D. A., Bagust, A., Haycox, A. & Walley, T., 1 Ion 2000, Yn: Value in Health. 3, 5, t. 373
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
Projectau
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01/08/2023 – 15/08/2028 (Wrthi'n gweithredu)
-
AWTTC health economics support in relation to the assessment of new medicines
01/05/2023 – 15/04/2025 (Wrthi'n gweithredu)
-
Wales Cancer Research Centre - funded extension for 2023-2025
01/04/2023 – 15/04/2025 (Wrthi'n gweithredu)
-
STAR-JIA (Steroid TreAtment TRialSteroid TreAtment TRial in Juvenile Idiopathic Arthritis)
01/01/2023 – 15/01/2027 (Wrthi'n gweithredu)
-
GeneGut: RNA technologies for Crohns disease
01/10/2022 – 31/10/2026 (Wrthi'n gweithredu)
-
KESS II MRes with Aparito BUK2E027
01/08/2022 – 31/03/2024 (Wedi gorffen)
-
Evaluating clinical implementation of the CARiAD intervention
01/04/2022 – 01/08/2022 (Wedi gorffen)
-
Senior Researcher Leaders 2022-25 - Year 1 2022-2023
01/04/2022 – 15/04/2025 (Wrthi'n gweithredu)
-
01/03/2022 – 28/02/2023 (Wedi gorffen)
-
01/02/2022 – 15/02/2027 (Wrthi'n gweithredu)
-
Cost-effectiveness of a pharmacogenetic panel test
01/01/2022 – 01/08/2022 (Wedi gorffen)
-
01/12/2021 – 31/08/2023 (Wedi gorffen)
-
01/10/2021 – 15/10/2027 (Wrthi'n gweithredu)
-
Un-CoV-er: Understanding the impact of SARS-CoV-2 infection in patients with blood cancer
01/10/2021 – 15/10/2026 (Wrthi'n gweithredu)
-
Mainstreaming genetic commissioning model for WHSCC
01/03/2021 – 01/08/2022 (Wedi gorffen)
-
22/02/2021 – 01/08/2022 (Wedi gorffen)
-
HEAL-COVID: HElping Alleviate the Longer-term consequences of COVID-19
01/02/2021 – 30/06/2024 (Wedi gorffen)
-
01/01/2021 – 15/07/2025 (Wrthi'n gweithredu)
-
01/07/2020 – 01/08/2022 (Wedi gorffen)
-
HTA of pharmacogenetics in Wales
01/07/2020 – 01/08/2022 (Wedi gorffen)
-
War-PATH (warfarin anticoagulation in patients with cardiovasculardisease in Sub-Saharan Africa)
01/06/2020 – 01/08/2022 (Wedi gorffen)
-
Warfarin Global Health Research Group (War-PATH) sub-contract
06/01/2020 – 30/11/2021 (Wedi gorffen)
-
Identifying variation in prescribing in BCUHB
01/09/2019 – 15/04/2021 (Wedi gorffen)
-
Trials Methodology Research Partnership
01/06/2019 – 01/08/2022 (Wedi gorffen)
-
H&CRW Senior Research Leaders Competition (year 1 of 3)
01/04/2019 – 01/08/2022 (Wedi gorffen)
-
01/03/2019 – 31/03/2024 (Wedi gorffen)
-
01/03/2019 – 30/04/2024 (Wedi gorffen)
-
Developing patient-centred, feasible alternative care for emergency department users with epilepsy
01/02/2019 – 01/08/2022 (Wedi gorffen)
-
The EXPO trial: Extended-release Pharmacotherapy for Opioid Use Disorder (EXPO):
01/01/2019 – 31/08/2024 (Wedi gorffen)
-
Health technology assessment of advanced (cell and gene) therapies
01/10/2018 – 31/07/2020 (Wedi gorffen)
-
AWTTC health economics support in relation to the assessment of new medicines
01/04/2018 – 30/09/2023 (Wedi gorffen)
Cysylltau:
-
RAPID (Phase IIb randomised double-blind placebo-controlled multi-centre trial)
01/01/2018 – 15/09/2024 (Wedi gorffen)
-
COPE: The Carboprost or Oxytocin for Postpartum haemorrhage Effectiveness study
01/09/2017 – 15/10/2024 (Wedi gorffen)
-
Developing a repurposed medicine for Duchenne muscular dystrophy
01/08/2017 – 01/08/2019 (Wedi gorffen)
Disgrifiad
Repurposing is taking a drug which is already approved for one disease and using it to treat another. Drugs which have been developed or approved for other uses have already been tested in humans, so detailed information is available on their pharmacology, formulation and potential toxicity. Because repurposing/repositioning builds upon previous research and development efforts, new candidate therapies could be ready for clinical trials quickly, speeding their review by Regulatory Authorities and, if approved, their integration into treatment for Duchenne.
Cysylltau:
-
HEAPS2: Health Economics Analysis Plans: devising content guidance through consensus
01/06/2017 – 01/08/2019 (Wedi gorffen)
-
CASTLE (Changing agendas on sleep, treatment & learning in epilepsy)
01/05/2017 – 31/10/2024 (Wedi gorffen)
Disgrifiad
The CASTLE study is focused on rolandic epilepsy, which is the most common type of childhood epilepsy and affects about one-sixth of all children with epilepsy in the UK.
Throughout the CASTLE study, we’ll be working with children, parents, doctors and nurses to choose the best ways to measure health and quality of life for children with epilepsy. The research will also include talking to parents and children about their experiences in relation to sleep, taking medication, learning and how taking part in the study has impacted on them.
Cysylltau:
-
Cost of illness study for Neuromyelitis optica (NMO)
01/04/2017 – 01/08/2019 (Wedi gorffen)
-
KESS II MRes with MC Diagnostics Ltd- BUK2116
01/02/2017 – 01/08/2022 (Wedi gorffen)
-
SUMMIT: Diabetes and mobile health technology
01/01/2017 – 15/08/2024 (Wedi gorffen)
Disgrifiad
Type 2 diabetes affects 2.9 million people in the UK. Treatments to reduce risks of complications from type 2 diabetes are effective if taken as intended. Concerns about medicines and difficulties in taking them regularly, whether intentional or unintentional, are common. In addition to the burden of preventable death and disability, the cost of non-adherence with diabetes treatments has been estimated at £100 million a year in avoidable treatment costs. Some services to help support people with making better use of their medicines are available, but evidence of their effectiveness and cost-effectiveness is weak. Understanding and improving this situation could make a major contribution to health and NHS costs.
There is some evidence that using brief messages to support people with better use of their medicines can be effective. This is especially in the context of tailored and personalised interventions using electronic health record data. However, more work is needed to develop such messages, embed them in health care delivery systems, and test whether they work when used at a wide scale.
This programme of work will bring together an interdisciplinary team to deliver a series of linked studies to address the way that digital technologies can be linked to state-of-the-art health psychology for personalised support in type 2 diabetes. Patients, clinicians and experts in behaviour change will be asked what sort of messages are likely to be relevant and acceptable for people starting and continuing taking a diabetes medicine. Predictors of non-adherence in a retrospective primary-care cohort will be examined using routinely collected electronic health record data. Qualitative methods will be used to explore the added value of tailored messages based on personal preferences, the type of medication prescribed, duration of treatment and timing of medication collection using real-time electronic health record data. The intervention will be tested in a randomised clinical trial and linked health economic study to estimate the extent of benefit and costs. A process evaluation, using mixed methods will inform understanding of how the intervention might work and be implemented within health care.
If effective, this technology could reduce the burden of complications and increased costs associated with under-use of diabetes medicines. A coordinated system for interacting with patients, including automated and personalised support messages could improve satisfaction with health services and offer a model for technology-based self-management. This approach could be extended to other aspects of diabetes care, and other long-term conditions.
Cysylltau:
-
PETReA (therapy in high tumour burden follicular lymphoma)
01/11/2016 – 31/12/2024 (Wrthi'n gweithredu)
-
CF-START (Cystic Fibrosis [CF] anti-staphylococcal antibiotic prophylaxis trial)
01/08/2016 – 31/08/2028 (Wrthi'n gweithredu)
Disgrifiad
The aim of the CF START trial is determine the safest and most effective way to treat infants diagnosed with Cystic Fibrosis (CF) with antibiotics. At the moment infants in the UK are prescribed an antibiotic, usually flucloxacillin, every day to prevent infection with a bacteria (bug) called Staphylococcus aureus (SA).
Although this approach appears to help prevent SA infection, there is a worry that it may make earlier infection with other bugs, such as Pseudomonas aeruginosa (PsA) more likely.
This trial is designed to test if infants with CF are more likely to get an earlier infection from PsA if they are taking flucloxacillin on a daily basis (“Prevent and Treat”) or Antibiotics in a more targeted manner (“Detect and Treat”).
Cysylltau:
-
Health economic analysis of the adoption of all Wales prescribing guidelines for asthma and COPD
01/08/2016 – 08/02/2017 (Wedi gorffen)
-
01/07/2016 – 17/07/2017 (Wedi gorffen)
-
EN-PNS (External non invasive peripheral nerve stimulation)
01/06/2016 – 30/08/2020 (Wedi gorffen)
-
AWTTC 2016-17 health economics support in relation to the assessment of new medicines
01/04/2016 – 18/05/2018 (Wedi gorffen)
Cysylltau:
-
Health Economics of use of ferrous iron salts in primary care in the UK
01/04/2016 – 31/01/2017 (Wedi gorffen)
-
Health Economics of use of ferrous iron salts in primary care in the UK
01/04/2016 – 03/01/2018 (Wedi gorffen)
-
Senior Research Leaders Group Membership
01/04/2016 – 09/07/2020 (Wedi gorffen)
-
PhD Studentship (pharmacometric-pharmacoeconomic analyses)
01/11/2015 – 01/08/2019 (Wedi gorffen)
-
Opt-Life (Optimising quality of living with a disabling neurological condition)
01/10/2015 – 01/08/2019 (Wedi gorffen)
Cysylltau:
-
Clinical Trials Unit Infrastructure Support Funding (extension to F008035)
01/09/2015 – 01/08/2022 (Wedi gorffen)
Cysylltau:
-
SAFE (Seizure first Aid training For Epilepsy)
01/05/2015 – 01/08/2019 (Wedi gorffen)
Cysylltau:
-
Workshop: Mapping current usage of Health Economic Analysis Plans (HEAPs)
01/05/2015 – 16/08/2017 (Wedi gorffen)
-
Research Design Service for the North West
01/04/2015 – 01/08/2019 (Wedi gorffen)
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Identification of items for inclusion in a standardised resource-use measure
01/02/2015 – 07/09/2016 (Wedi gorffen)
Cysylltau:
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HLA panel for adverse drug reactions
15/01/2015 – 11/08/2017 (Wedi gorffen)
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ROAM (surgical resection of Atypical Meningioma)
01/11/2014 – 30/09/2024 (Wedi gorffen)
Disgrifiad
ROAM is a multi-centre, randomised controlled trial. The trial will randomise patients who have undergone gross total surgical resection of atypical (grade II) meningioma to receive either early adjuvant fractionated radiotherapy for 6 weeks (intervention) or active monitoring (comparator).
The trial is funded by the National Institute for Health Research's Health Technology Assessment Programme (NIHR HTA) and is sponsored by The Walton Centre NHS Foundation Trust. The day-to-day running of the trial, monitoring and analysis is being coordinated by a team at the Clinical Trials Research Centre (CTRC) at University of Liverpool. The data management aspect of the trial will be managed by The European Organisation for Research and Treatment of Cancer (EORTC), Belgium.
Cysylltau:
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01/07/2014 – 31/05/2020 (Wedi gorffen)
Disgrifiad
MYPAN is a research study. In this study we want to see if a medicine called Mycophenolate mofetil (MMF) is as good as the normal medicine doctors use for vasculitis called cyclophosphamide (CYC).
MYPAN is an international trial that will be conducted in several countries including the United Kingdom, Belgium, Croatia, Czech Republic, Germany, Greece, Italy, Netherlands, Portugal, France, Spain, Sweden and Turkey.
Cysylltau:
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NERVES (effectiveness of trans-foraminal epidural steroid injections)
01/07/2014 – 01/08/2019 (Wedi gorffen)
Cysylltau:
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AWTTC health economics support in relation to the assessment of new medicines
01/04/2014 – 31/03/2016 (Wedi gorffen)
Cysylltau:
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DIRUM - Database of Instruments for Resource Use Measurement
01/01/2014 – 15/08/2014 (Wedi gorffen)
Cysylltau:
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North West Hub for Trials Methodology Research[extension to r26004]
01/10/2013 – 01/08/2019 (Wedi gorffen)
Cysylltau:
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Community diarrhoeal disease clusters and outbreaks
01/04/2013 – 01/08/2019 (Wedi gorffen)
Cysylltau:
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01/12/2012 – 01/08/2019 (Wedi gorffen)
Cysylltau:
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NIHR Clinical Trials Fellowship 2012
01/11/2012 – 01/08/2014 (Wedi gorffen)
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Methods for risk (harm) benefit analysis
01/10/2012 – 01/08/2022 (Wedi gorffen)
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01/06/2012 – 20/04/2020 (Wedi gorffen)
Cysylltau:
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DIRUM systematic review project
01/03/2012 – 23/08/2013 (Wedi gorffen)
Cysylltau:
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01/11/2011 – 01/08/2022 (Wedi gorffen)
Cysylltau:
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Systematic reviews and economic evaluations in epilepsy
01/04/2011 – 28/02/2016 (Wedi gorffen)
Cysylltau:
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Develop central repository for trial-based health economic evaluations
01/01/2011 – 09/03/2012 (Wedi gorffen)
Cysylltau:
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Effectiveness of adalumimab in the treatment of paediatric uveitis
01/01/2011 – 19/03/2018 (Wedi gorffen)
Cysylltau:
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Patient preferences and priorities for treatment options and outcomes in epilepsy
01/01/2011 – 10/02/2016 (Wedi gorffen)
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Randomised controlled study of insulin delivered as continuous subcutaneous infusion
01/11/2010 – 27/04/2017 (Wedi gorffen)
Cysylltau:
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Research Design Service for the North West
01/04/2010 – 04/09/2015 (Wedi gorffen)
Cysylltau:
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CATCH (CATheter infections in CHildren)
01/01/2010 – 08/08/2016 (Wedi gorffen)
Cysylltau:
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Development of a preference-based health-related quality of life instrument for epilepsy
01/08/2009 – 28/03/2011 (Wedi gorffen)
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Ascertaining Barriers for Compliance (ABC)
01/01/2009 – 23/09/2013 (Wedi gorffen)
Cysylltau:
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01/10/2008 – 30/09/2013 (Wedi gorffen)
Cysylltau:
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01/10/2008 – 21/08/2014 (Wedi gorffen)
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Clinical Trials Unit Infrastructure Support Funding - Clinical Trials Research Centre
01/09/2008 – 01/08/2014 (Wedi gorffen)
Cysylltau:
-
01/09/2008 – 01/08/2022 (Wedi gorffen)
Cysylltau:
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NIHR Research Development Service North West (NIHR RDS NW)
01/04/2008 – 01/08/2010 (Wedi gorffen)
Cysylltau:
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Health Economics Support In Relation
01/04/2007 – 01/08/2013 (Wedi gorffen)
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Cost-Effectiveness Of Pre-Prescription
01/01/2007 – 10/09/2013 (Wedi gorffen)
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Development Of An Economic Model
01/03/2006 – 31/07/2010 (Wedi gorffen)